Pimagedine

Pimagedine

SCHEMBL7117351

N=C(N)NN.O=c1[nH]cc([N+](=O)[O-])c(=O)[nH]1

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.41
ALDH1A1 P00352 4/20 0.41
KLF10 Q13118 1/20 0.41
GAA P10253 2/20 0.37
MAPT P10636 4/20 0.35
TSHR P16473 2/20 0.35
CYP1A2 P05177 2/20 0.35
GRIA1 P42261 2/20 0.35
GRIA2 P42262 2/20 0.35
GRIA4 P48058 2/20 0.35
GRIK5 Q16478 2/20 0.35
GRIN2D O15399 1/20 0.35
GRIN3B O60391 1/20 0.35
CYP3A4 P08684 1/20 0.35
HPGD P15428 1/20 0.35
GRIK1 P39086 1/20 0.35
GRIA3 P42263 1/20 0.35
BLM P54132 1/20 0.35
GRIN1 Q05586 1/20 0.35
GRIN2A Q12879 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Guanidine SCHEMBL7115879 0.91 LMNA (0.41) LMNAALDH1A1KLF10GAAMAPT
Hydrazine SCHEMBL7121815 0.84 LMNA (0.44) LMNAALDH1A1KLF10GAAMAPT
SCHEMBL190925 0.83 LMNA (0.47) LMNAALDH1A1KLF10GAAMAPT
Ammonia Solution, Strong SCHEMBL7123914 0.82 LMNA (0.45) LMNAALDH1A1KLF10GAAMAPT
SCHEMBL7122106 0.75 LMNA (0.36) LMNAALDH1A1KLF10GAAMAPT
SCHEMBL7122109 0.75 LMNA (0.36) LMNAALDH1A1KLF10GAAMAPT
SCHEMBL7225377 0.72 KDM4E (0.40) LMNAALDH1A1KLF10GAAMAPT
T-Butylacetic Acid SCHEMBL10005013 0.70 LMNA (0.41) LMNAALDH1A1KLF10GAAMAPT
T-Butylacetic Acid SCHEMBL21570799 0.70 LMNA (0.41) LMNAALDH1A1KLF10GAAMAPT
Pimagedine SCHEMBL4219664 0.68 GPR35 (0.44) ALDH1A1GAAMAPTCYP1A2HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6589375-B2 Using basic copper nitrate as oxidizer TALLEY DEFENSE SYSTEMS, INC. 2003-07-08 US claimed
US-20030094225-A1 LOW SOLIDS GAS GENERANT HAVING A LOW FLAME TEMPERATURE TALLY DEFENSE SYSTEMS, INC. 2003-05-22 US claimed
US-6589375-B2 Using basic copper nitrate as oxidizer TALLEY DEFENSE SYSTEMS, INC. 2003-07-08 US disclosed
US-6589375-B2 Using basic copper nitrate as oxidizer TALLEY DEFENSE SYSTEMS, INC. 2003-07-08 US disclosed
US-20030094225-A1 LOW SOLIDS GAS GENERANT HAVING A LOW FLAME TEMPERATURE TALLY DEFENSE SYSTEMS, INC. 2003-05-22 US disclosed
US-20030094225-A1 LOW SOLIDS GAS GENERANT HAVING A LOW FLAME TEMPERATURE TALLY DEFENSE SYSTEMS, INC. 2003-05-22 US disclosed