Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 12/20 | 0.42 |
| ▸ | MAOB | P27338 | 3/20 | 0.39 |
| ▸ | GCK | P35557 | 3/20 | 0.39 |
| ▸ | PDE5A | O76074 | 1/20 | 0.36 |
| ▸ | PDE1A | P54750 | 1/20 | 0.36 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.36 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL192244 | 0.78 | GCK (0.44) | AOC3MAOBGCKPDE5APDE1A | |
| SCHEMBL190604 | 0.78 | GAA (0.43) | AOC3MAOBGCKPDE5APDE1A | |
| Hydrochloric Acid SCHEMBL191165 | 0.77 | GCK (0.43) | AOC3MAOBGCKPDE5APDE1A | |
| SCHEMBL191430 | 0.76 | LMNA (0.46) | — | |
| SCHEMBL191596 | 0.76 | GCK (0.44) | AOC3MAOBGCKPDE5APDE1A | |
| SCHEMBL190932 | 0.75 | AOC3 (0.40) | AOC3MAOBGCKPDE5AHDAC1 | |
| SCHEMBL190933 | 0.75 | GCK (0.41) | AOC3MAOBGCKHDAC1HDAC6 | |
| SCHEMBL27741187 | 0.75 | AOC3 (0.41) | AOC3MAOBGCKHDAC1HDAC6 | |
| SCHEMBL191341 | 0.74 | MEN1 (0.43) | GCK | |
| SCHEMBL191480 | 0.73 | GCK (0.54) | AOC3GCKHDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1986645-B1 | GLUCOKINASE ACTIVATORS | ARRAY BIOPHARMA INC (US) | 2012-01-04 | — | — | EP | disclosed |