Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19085497 | 0.74 | — | — | |
| SCHEMBL23110249 | 0.74 | BRS3 (0.31) | — | |
| SCHEMBL680605 | 0.73 | — | — | |
| SCHEMBL21302162 | 0.73 | HPGD (0.44) | HPGDTSHRLMNA | |
| Bromide SCHEMBL28471242 | 0.71 | — | — | |
| SCHEMBL20696522 | 0.71 | HPGD (0.42) | HPGDTSHRLMNA | |
| SCHEMBL12012896 | 0.70 | — | — | |
| SCHEMBL20468593 | 0.69 | — | — | |
| SCHEMBL7179426 | 0.69 | TAAR1 (0.34) | — | |
| SCHEMBL12993678 | 0.69 | SHBG (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9701680-B2 | Pyrimidine and pyridine compounds and their usage | HUTCHISON MEDIPHARMA LIMITED (CN) | 2017-07-11 | — | — | US | disclosed |