Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5B | Q9UGL1 | 12/20 | 0.66 |
| ▸ | KDM5A | P29375 | 5/20 | 0.66 |
| ▸ | KDM6B | O15054 | 3/20 | 0.54 |
| ▸ | KDM4C | Q9H3R0 | 6/20 | 0.50 |
| ▸ | KDM4A | O75164 | 3/20 | 0.50 |
| ▸ | KDM2B | Q8NHM5 | 4/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19101706 | 0.81 | KDM5A (0.67) | KDM5BKDM5AKDM4CKDM4AKDM2B | |
| SCHEMBL16033515 | 0.80 | KDM5A (1.00) | KDM5BKDM5AKDM4CKDM4AKDM2B | |
| SCHEMBL18579569 | 0.78 | KDM5B (0.62) | KDM5BKDM5AKDM6BKDM4CKDM4A | |
| SCHEMBL19101701 | 0.78 | KDM4C (0.47) | KDM5BKDM5AKDM6BKDM4CKDM4A | |
| SCHEMBL26209086 | 0.75 | KDM6B (0.62) | KDM5BKDM5AKDM6BKDM4CKDM4A | |
| SCHEMBL19383316 | 0.74 | KDM5B (0.69) | KDM5BKDM5AKDM6BKDM4CKDM4A | |
| SCHEMBL17891718 | 0.73 | KDM6B (0.64) | KDM5BKDM5AKDM6BKDM4CKDM2B | |
| SCHEMBL19139044 | 0.72 | KDM2B (0.47) | KDM5BKDM5AKDM4CKDM4AKDM2B | |
| SCHEMBL19383303 | 0.72 | KDM5B (0.63) | KDM5BKDM5AKDM6BKDM4CKDM4A | |
| SCHEMBL17898932 | 0.71 | KDM6B (0.62) | KDM5BKDM5AKDM6BKDM4CKDM2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9701657-B2 | Histone demethylase inhibitors | CELGENE QUANTICEL RESEARCH, INC. (US) | 2017-07-11 | — | — | US | disclosed |