Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM2B | Q8NHM5 | 6/20 | 0.47 |
| ▸ | KDM5A | P29375 | 9/20 | 0.46 |
| ▸ | KDM5B | Q9UGL1 | 9/20 | 0.46 |
| ▸ | KDM4C | Q9H3R0 | 13/20 | 0.45 |
| ▸ | KDM4A | O75164 | 5/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19101701 | 0.88 | KDM4C (0.47) | KDM2BKDM5AKDM5BKDM4CKDM4A | |
| SCHEMBL19101674 | 0.88 | KDM4C (0.46) | KDM2BKDM5AKDM5BKDM4CKDM4A | |
| SCHEMBL19101734 | 0.87 | KDM2B (0.41) | KDM2BKDM5AKDM5BKDM4CKDM4A | |
| SCHEMBL19101737 | 0.86 | KDM2B (0.40) | KDM2BKDM5AKDM5BKDM4CKDM4A | |
| SCHEMBL19102093 | 0.85 | KDM2B (0.41) | KDM2BKDM5AKDM5BKDM4CKDM4A | |
| SCHEMBL16033410 | 0.80 | KDM2B (0.74) | KDM2BKDM5AKDM5BKDM4CKDM4A | |
| SCHEMBL19101706 | 0.75 | KDM5A (0.67) | KDM2BKDM5AKDM5BKDM4CKDM4A | |
| SCHEMBL18612739 | 0.74 | KDM4C (0.71) | KDM2BKDM5AKDM5BKDM4CKDM4A | |
| SCHEMBL18612958 | 0.73 | KDM2B (0.69) | KDM2BKDM5AKDM5BKDM4CKDM4A | |
| SCHEMBL18612971 | 0.73 | KDM4C (0.71) | KDM2BKDM5AKDM5BKDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9701657-B2 | Histone demethylase inhibitors | CELGENE QUANTICEL RESEARCH, INC. (US) | 2017-07-11 | — | — | US | disclosed |