Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 7/20 | 0.67 |
| ▸ | KDM5B | Q9UGL1 | 7/20 | 0.67 |
| ▸ | KDM4C | Q9H3R0 | 9/20 | 0.52 |
| ▸ | KDM4A | O75164 | 4/20 | 0.52 |
| ▸ | PHF8 | Q9UPP1 | 7/20 | 0.47 |
| ▸ | KDM2B | Q8NHM5 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18579762 | 0.81 | KDM5A (0.67) | KDM5AKDM5BKDM4CKDM4APHF8 | |
| SCHEMBL19101682 | 0.81 | KDM5B (0.66) | KDM5AKDM5BKDM4CKDM4AKDM2B | |
| SCHEMBL16034016 | 0.81 | KDM5A (1.00) | KDM5AKDM5BKDM4CKDM4AKDM2B | |
| SCHEMBL16034331 | 0.77 | KDM5B (0.77) | KDM5AKDM5BKDM4CKDM4APHF8 | |
| SCHEMBL19101675 | 0.76 | KDM4C (0.52) | KDM5AKDM5BKDM4CKDM4APHF8 | |
| SCHEMBL19139044 | 0.75 | KDM2B (0.47) | KDM5AKDM5BKDM4CKDM4AKDM2B | |
| SCHEMBL19101681 | 0.75 | KDM4C (0.44) | KDM5AKDM5BKDM4CKDM4APHF8 | |
| SCHEMBL19101685 | 0.75 | PHF8 (0.48) | KDM5AKDM5BKDM4CKDM4APHF8 | |
| SCHEMBL24244130 | 0.74 | KDM5A (0.66) | KDM5AKDM5BKDM4CKDM4APHF8 | |
| SCHEMBL19383523 | 0.73 | KDM5B (0.64) | KDM5AKDM5BKDM4CKDM4APHF8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9701657-B2 | Histone demethylase inhibitors | CELGENE QUANTICEL RESEARCH, INC. (US) | 2017-07-11 | — | — | US | disclosed |