Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM2B | Q8NHM5 | 4/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 13/20 | 0.40 |
| ▸ | KDM5A | P29375 | 8/20 | 0.40 |
| ▸ | KDM5B | Q9UGL1 | 7/20 | 0.40 |
| ▸ | KDM4A | O75164 | 3/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.35 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19139044 | 0.87 | KDM2B (0.47) | KDM2BKDM4CKDM5AKDM5BKDM4A | |
| SCHEMBL19101737 | 0.86 | KDM2B (0.40) | KDM2BKDM4CKDM5AKDM5BKDM4A | |
| SCHEMBL16033404 | 0.83 | KDM2B (0.64) | KDM2BKDM4CKDM5AKDM5BKDM4A | |
| SCHEMBL19101674 | 0.82 | KDM4C (0.46) | KDM2BKDM4CKDM5AKDM5BKDM4A | |
| SCHEMBL19101701 | 0.78 | KDM4C (0.47) | KDM2BKDM4CKDM5AKDM5BKDM4A | |
| SCHEMBL19102093 | 0.76 | KDM2B (0.41) | KDM2BKDM4CKDM5AKDM5BKDM4A | |
| SCHEMBL17710646 | 0.75 | KDM2B (0.41) | KDM2BKDM4CKDM5AKDM5BKDM4A | |
| SCHEMBL19101675 | 0.72 | KDM4C (0.52) | KDM2BKDM4CKDM5AKDM5BKDM4A | |
| SCHEMBL16033654 | 0.70 | KDM2B (0.61) | KDM2BKDM4CKDM5AKDM5BKDM4A | |
| SCHEMBL16033410 | 0.69 | KDM2B (0.74) | KDM2BKDM4CKDM5AKDM5BKDM4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9701657-B2 | Histone demethylase inhibitors | CELGENE QUANTICEL RESEARCH, INC. (US) | 2017-07-11 | — | — | US | disclosed |