Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 11/20 | 0.52 |
| ▸ | KDM5A | P29375 | 8/20 | 0.52 |
| ▸ | KDM5B | Q9UGL1 | 8/20 | 0.52 |
| ▸ | KDM2B | Q8NHM5 | 3/20 | 0.46 |
| ▸ | PHF8 | Q9UPP1 | 6/20 | 0.45 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.45 |
| ▸ | KDM4A | O75164 | 4/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19101681 | 0.88 | KDM4C (0.44) | KDM4CKDM5AKDM5BKDM2BPHF8 | |
| SCHEMBL19101685 | 0.86 | PHF8 (0.48) | KDM4CKDM5AKDM5BKDM2BPHF8 | |
| SCHEMBL19101736 | 0.86 | KDM4A (0.53) | KDM4CPHF8KDM4A | |
| SCHEMBL16033844 | 0.82 | KDM4C (0.77) | KDM4CKDM5AKDM5BKDM2BKDM4A | |
| SCHEMBL19101706 | 0.76 | KDM5A (0.67) | KDM4CKDM5AKDM5BKDM2BPHF8 | |
| SCHEMBL19101734 | 0.72 | KDM2B (0.41) | KDM4CKDM5AKDM5BKDM2BPHF8 | |
| SCHEMBL19139044 | 0.72 | KDM2B (0.47) | KDM4CKDM5AKDM5BKDM2BKDM4A | |
| SCHEMBL16033534 | 0.72 | KDM5A (0.65) | KDM4CKDM5AKDM5BKDM2BKDM4A | |
| SCHEMBL17604502 | 0.71 | PHF8 (0.59) | KDM4CKDM5AKDM5BKDM2BPHF8 | |
| SCHEMBL16075704 | 0.71 | KDM5A (0.76) | KDM4CKDM5AKDM5BKDM2BKDM4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9701657-B2 | Histone demethylase inhibitors | CELGENE QUANTICEL RESEARCH, INC. (US) | 2017-07-11 | — | — | US | disclosed |