Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 2/20 | 0.46 |
| ▸ | POLRMT | O00411 | 1/20 | 0.42 |
| ▸ | GAPDH | P04406 | 3/20 | 0.41 |
| ▸ | DOT1L | Q8TEK3 | 2/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.41 |
| ▸ | SLC28A2 | O43868 | 2/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.41 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | STAT6 | P42226 | 1/20 | 0.41 |
| ▸ | PI4KA | P42356 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.41 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24982409 | 1.00 | HIF1A (0.46) | HIF1APOLRMTGAPDHDOT1LADORA3 | |
| SCHEMBL25008855 | 1.00 | HIF1A (0.46) | HIF1APOLRMTGAPDHDOT1LADORA3 | |
| SCHEMBL16710417 | 1.00 | HIF1A (0.46) | HIF1APOLRMTGAPDHDOT1LADORA3 | |
| SCHEMBL24982322 | 1.00 | HIF1A (0.46) | HIF1APOLRMTGAPDHDOT1LADORA3 | |
| SCHEMBL10154369 | 1.00 | HIF1A (0.46) | HIF1APOLRMTGAPDHDOT1LADORA3 | |
| SCHEMBL22381795 | 0.90 | POLRMT (0.41) | HIF1APOLRMTGAPDHDOT1LADORA3 | |
| SCHEMBL16479516 | 0.89 | POLRMT (0.40) | HIF1APOLRMTGAPDHDOT1LADORA3 | |
| SCHEMBL881562 | 0.89 | POLRMT (0.40) | HIF1APOLRMTGAPDHDOT1LADORA3 | |
| SCHEMBL806951 | 0.89 | POLRMT (0.40) | HIF1APOLRMTGAPDHDOT1LADORA3 | |
| SCHEMBL19101901 | 0.89 | POLRMT (0.40) | HIF1APOLRMTGAPDHDOT1LADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11701372-B2 | Inhalation formulations of 1'-cyano substituted carba-nucleoside analogs | GILEAD SCIENCES, INC. (US) | 2023-07-18 | — | — | US | disclosed |
| US-9701682-B2 | Pyrrolo[1,2-f][1,2,4]triazines useful for treating respiratory syncitial virus infections | GILEAD SCIENCES, INC. (US) | 2017-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11701372-B2 | Inhalation formulations of 1'-cyano substituted carba-nucleoside analogs | SLC29A1, SLC28A1, SLC29A2 | HIF1A 1471/4885POLRMT 75/4885GAPDH 1585/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.