Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACVRL1 | P37023 | 10/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 8/20 | 0.35 |
| ▸ | TNK2 | Q07912 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20756113 | 1.00 | ACVRL1 (0.36) | ACVRL1PIK3CDTNK2 | |
| SCHEMBL19101852 | 0.92 | ACVRL1 (0.35) | ACVRL1PIK3CDTNK2 | |
| SCHEMBL16698622 | 0.76 | ACVRL1 (0.39) | ACVRL1PIK3CD | |
| SCHEMBL16698811 | 0.75 | ACVRL1 (0.39) | ACVRL1PIK3CD | |
| SCHEMBL19779074 | 0.74 | POLRMT (0.38) | — | |
| Phosphoric Acid SCHEMBL21082020 | 0.73 | PIK3CD (0.37) | ACVRL1PIK3CDTNK2 | |
| Phosphoric Acid SCHEMBL16701315 | 0.73 | PIK3CD (0.36) | ACVRL1PIK3CDTNK2 | |
| SCHEMBL20756525 | 0.73 | POLRMT (0.34) | ACVRL1PIK3CD | |
| SCHEMBL23959981 | 0.72 | ACVRL1 (0.41) | ACVRL1PIK3CD | |
| SCHEMBL23959982 | 0.71 | ACVRL1 (0.42) | ACVRL1PIK3CDTNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9701682-B2 | Pyrrolo[1,2-f][1,2,4]triazines useful for treating respiratory syncitial virus infections | GILEAD SCIENCES, INC. (US) | 2017-07-11 | — | — | US | disclosed |