Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | SCN10A | Q9Y5Y9 | 6/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TYR | P14679 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | METAP2 | P50579 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | KIT | P10721 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4548606 | 0.80 | SCN10A (0.39) | ALDH1A1HPGDALOX15HSD17B10TDP1 | |
| SCHEMBL18177013 | 0.80 | SCN10A (0.39) | ALDH1A1HPGDALOX15HSD17B10TDP1 | |
| SCHEMBL179533 | 0.79 | LCK (0.52) | ALDH1A1MAPTMEN1KMT2AGAA | |
| SCHEMBL14044797 | 0.76 | SCN10A (0.37) | ALDH1A1HPGDALOX15HSD17B10TDP1 | |
| SCHEMBL20047540 | 0.76 | SCN10A (0.38) | ALDH1A1HPGDALOX15HSD17B10TDP1 | |
| SCHEMBL25449364 | 0.76 | LCK (0.41) | SCN10AKCNH2METAP2LCKKDR | |
| SCHEMBL14239550 | 0.76 | CYP1A2 (0.48) | ALDH1A1MAPTMEN1KMT2APKM | |
| SCHEMBL12755251 | 0.74 | ALDH1A1 (0.45) | ALDH1A1HPGDALOX15HSD17B10TDP1 | |
| SCHEMBL22393717 | 0.73 | SCN10A (0.38) | SCN10AKCNH2SMN1; SMN2LCKKIT | |
| SCHEMBL12755258 | 0.73 | PIK3CA (0.54) | MAPTMEN1KMT2ASCN10ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9700543-B2 | GLP-1 receptor stabilizers and modulators | CELGENE INTERNATIONAL II SÀRL (CH) | 2017-07-11 | — | — | US | disclosed |