Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 7/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | IDH1 | O75874 | 1/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.38 |
| ▸ | KDM1A | O60341 | 5/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19110853 | 1.00 | KCNK3 (0.44) | KCNK3SIGMAR1IDH1ENPP2KDM1A | |
| SCHEMBL19110855 | 0.93 | KCNK3 (0.43) | KCNK3SIGMAR1IDH1ENPP2LMNA | |
| SCHEMBL19110857 | 0.93 | KCNK3 (0.43) | KCNK3SIGMAR1IDH1ENPP2LMNA | |
| SCHEMBL19110854 | 0.90 | KCNK3 (0.40) | KCNK3SIGMAR1KDM1AMAOBSMN1; SMN2 | |
| SCHEMBL17328191 | 0.88 | KCNK3 (0.43) | KCNK3SIGMAR1IDH1ENPP2DPP4 | |
| SCHEMBL17317616 | 0.88 | KCNK3 (0.43) | KCNK3SIGMAR1IDH1ENPP2DPP4 | |
| SCHEMBL17328198 | 0.88 | KCNK3 (0.43) | KCNK3SIGMAR1IDH1ENPP2DPP4 | |
| SCHEMBL19110719 | 0.87 | ENPP2 (0.46) | KCNK3SIGMAR1IDH1ENPP2 | |
| SCHEMBL19110838 | 0.85 | KCNK3 (0.41) | KCNK3SIGMAR1IDH1ENPP2KDM1A | |
| SCHEMBL19110824 | 0.84 | KCNK3 (0.43) | KCNK3SIGMAR1IDH1ENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170197960-A1 | ATX MODULATING AGENTS | BIOGEN MA INC. | 2017-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170197960-A1 | ATX MODULATING AGENTS | ENPP2, ATXN10, ATXN2 | KCNK3 1825/4885SIGMAR1 2505/4885IDH1 3256/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.