Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.54 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.49 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.49 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 2/20 | 0.47 |
| ▸ | PPARA | Q07869 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.44 |
| ▸ | HPGDS | O60760 | 1/20 | 0.43 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LPL | P06858 | 1/20 | 0.39 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5018819 | 0.83 | LTA4H (0.61) | LTA4HCYP17A1CYP11B1CYP11B2PPARG | |
| SCHEMBL6850645 | 0.81 | LTA4H (0.65) | LTA4HCYP17A1CYP11B1CYP11B2PPARG | |
| SCHEMBL6868143 | 0.79 | LTA4H (0.53) | LTA4HCYP17A1CYP11B1CYP11B2PPARG | |
| SCHEMBL5765234 | 0.77 | LTA4H (0.68) | LTA4HCYP17A1CYP11B1CYP11B2PPARG | |
| SCHEMBL13819801 | 0.76 | LTA4H (0.53) | LTA4HCYP17A1CYP11B1CYP11B2PPARG | |
| SCHEMBL8283173 | 0.75 | TRPA1 (0.52) | PPARGPPARAFFAR1ALDH1A1 | |
| SCHEMBL14210015 | 0.75 | PPARG (0.62) | LTA4HCYP17A1CYP11B1CYP11B2PPARG | |
| SCHEMBL11824948 | 0.74 | LTA4H (0.54) | LTA4HCYP17A1CYP11B1CYP11B2PPARG | |
| SCHEMBL14672107 | 0.73 | LTA4H (0.58) | LTA4HCYP17A1CYP11B1CYP11B2PPARG | |
| SCHEMBL404521 | 0.73 | LTA4H (0.68) | LTA4HCYP17A1CYP11B1CYP11B2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2470514-B1 | PSEUDO-DIPEPTIDES AS MMP INHIBITORS | COMMISSARIAT L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2017-07-12 | — | — | EP | disclosed |