Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.34 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.34 |
| ▸ | CACNA1I | Q9P0X4 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 2/20 | 0.32 |
| ▸ | MAOA | P21397 | 2/20 | 0.32 |
| ▸ | MAOB | P27338 | 2/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1910829 | 0.89 | ALDH1A1 (0.33) | ALDH1A1HTTCACNA1GCACNA1HCACNA1I | |
| SCHEMBL1911093 | 0.89 | ALDH1A1 (0.33) | ALDH1A1HTTCACNA1GCACNA1HCACNA1I | |
| SCHEMBL319340 | 0.89 | ALDH1A1 (0.33) | ALDH1A1HTTCACNA1GCACNA1HCACNA1I | |
| SCHEMBL1911241 | 0.89 | MEN1 (0.33) | ALDH1A1HTTGAAPOLBSMN1; SMN2 | |
| SCHEMBL10278570 | 0.83 | ALDH1A1 (0.34) | ALDH1A1HTTCACNA1GCACNA1HCACNA1I | |
| SCHEMBL10278769 | 0.81 | MEN1 (0.33) | ALDH1A1HTTGAAPOLBMEN1 | |
| SCHEMBL319117 | 0.81 | ALDH1A1 (0.38) | ALDH1A1HTTCACNA1GCACNA1HCACNA1I | |
| SCHEMBL1910640 | 0.81 | ALDH1A1 (0.38) | ALDH1A1HTTCACNA1GCACNA1HCACNA1I | |
| SCHEMBL319625 | 0.81 | MEN1 (0.35) | ALDH1A1HTTPOLBMEN1KMT2A | |
| SCHEMBL14902742 | 0.80 | MEN1 (0.35) | ALDH1A1HTTGAAPOLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012004217-A1 | CYCLIC ETHER COMPOUNDS USEFUL AS KINASE INHIBITORS | NOVARTIS AG (CH) | 2012-01-12 | — | — | WO | disclosed |