SCHEMBL19112477

SCHEMBL19112477

N#CC1C(=O)NC(=O)[C@H](C#N)C12CCCCC2

nearest known ligand 0.44

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.44
GAA P10253 7/20 0.44
LMNA P02545 4/20 0.42
SMN1; SMN2 Q16637 3/20 0.42
MAPK1 P28482 1/20 0.42
MAPT P10636 3/20 0.37
KDM4E B2RXH2 1/20 0.37
TSHR P16473 3/20 0.37
HPGD P15428 1/20 0.37
USP2 O75604 2/20 0.34
TP53 P04637 2/20 0.34
HTT P42858 2/20 0.34
NOD2 Q9HC29 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL28039464 0.98 ALDH1A1 (0.43) ALDH1A1GAALMNASMN1; SMN2MAPK1
SCHEMBL8423510 0.98 ALDH1A1 (0.42) ALDH1A1GAALMNASMN1; SMN2MAPK1
SCHEMBL13082552 0.89 ALDH1A1 (0.43) ALDH1A1GAALMNASMN1; SMN2MAPK1
SCHEMBL23222397 0.84 ALDH1A1 (0.38) ALDH1A1GAALMNASMN1; SMN2MAPK1
SCHEMBL13259108 0.83 ALDH1A1 (0.37) ALDH1A1GAALMNASMN1; SMN2MAPK1
SCHEMBL2455236 0.83 ALDH1A1 (0.37) ALDH1A1GAALMNASMN1; SMN2MAPK1
SCHEMBL8776159 0.76 ALDH1A1 (0.41) ALDH1A1GAALMNASMN1; SMN2MAPK1
SCHEMBL9356254 0.73 ALDH1A1 (0.39) ALDH1A1GAALMNASMN1; SMN2MAPK1
SCHEMBL5856784 0.72 CYP2C9 (0.37) ALDH1A1GAAMAPK1MAPTTSHR
SCHEMBL6425505 0.71 ALDH1A1 (0.33) ALDH1A1GAALMNASMN1; SMN2MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3604272-A1 PROCESS FOR THE PREPARATION OF GABAPENTIN Divi's Laboratories Limited (IN) 2020-02-05 EP disclosed
EP-1939170-B1 PROCESS FOR THE PREPARATION OF GABAPENTIN HYDROCHLORIDE NHWA PHARMA CORP (CN) 2017-07-12 EP disclosed