Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.41 |
| ▸ | GAA | P10253 | 8/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | STAT6 | P42226 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8423510 | 0.77 | ALDH1A1 (0.42) | ALDH1A1GAAMAPTSMN1; SMN2LMNA | |
| SCHEMBL19112477 | 0.76 | ALDH1A1 (0.44) | ALDH1A1GAAMAPTSMN1; SMN2LMNA | |
| SCHEMBL2147312 | 0.74 | ALDH1A1 (0.36) | ALDH1A1GAASMN1; SMN2LMNAMAPK1 | |
| SCHEMBL13082552 | 0.70 | ALDH1A1 (0.43) | ALDH1A1GAAMAPTSMN1; SMN2LMNA | |
| SCHEMBL9356254 | 0.70 | ALDH1A1 (0.39) | ALDH1A1GAASMN1; SMN2LMNAMAPK1 | |
| SCHEMBL5856784 | 0.69 | CYP2C9 (0.37) | ALDH1A1GAAMAPTUSP2TSHR | |
| SCHEMBL6425505 | 0.68 | ALDH1A1 (0.33) | ALDH1A1GAASMN1; SMN2LMNAMAPK1 | |
| SCHEMBL6425510 | 0.68 | ALDH1A1 (0.33) | ALDH1A1GAASMN1; SMN2LMNAMAPK1 | |
| SCHEMBL6378618 | 0.68 | ALDH1A1 (0.33) | ALDH1A1GAASMN1; SMN2LMNAMAPK1 | |
| SCHEMBL7708743 | 0.66 | ALDH1A1 (0.35) | ALDH1A1GAAMAPTSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0570263-B1 | New alkene carboxylic acid derivatives, process for their preparation and pharmaceutic compositions containing them | ADIR (FR) | 1997-12-03 | — | — | EP | disclosed |
| US-5436343-A | Thromboxane A2 receptor antagonist, thromoboxane A2 synthase inhibitor | ADIR ET COMPAGNIE (FR) | 1995-07-25 | — | — | US | disclosed |
| EP-0621267-A1 | Spiropiperidine derivatives and their use as fungicides | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1994-10-26 | — | — | EP | disclosed |
| EP-0570263-A1 | New alkene carboxylic acid derivatives, process for their preparation and pharmaceutic compositions containing them | ADIR ET COMPAGNIE (FR) | 1993-11-18 | — | — | EP | disclosed |