Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | RORC | P51449 | 3/20 | 0.51 |
| ▸ | NR1H3 | Q13133 | 11/20 | 0.50 |
| ▸ | NR1H2 | P55055 | 10/20 | 0.50 |
| ▸ | RORA | P35398 | 2/20 | 0.46 |
| ▸ | MLYCD | O95822 | 3/20 | 0.44 |
| ▸ | RORB | Q92753 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL131990 | 0.81 | NR1H2 (0.68) | SMN1; SMN2NR1H3NR1H2MLYCD | |
| SCHEMBL6487024 | 0.78 | SMN1; SMN2 (0.61) | SMN1; SMN2RORCNR1H3NR1H2RORA | |
| Water SCHEMBL1684070 | 0.78 | NR1H2 (0.65) | SMN1; SMN2NR1H3NR1H2MLYCD | |
| SCHEMBL8462905 | 0.77 | LMNA (0.40) | SMN1; SMN2RORC | |
| SCHEMBL378918 | 0.77 | CA1 (0.54) | — | |
| SCHEMBL11626027 | 0.76 | SMN1; SMN2 (0.69) | SMN1; SMN2RORCRORAMLYCD | |
| SCHEMBL12403856 | 0.75 | SMN1; SMN2 (0.58) | SMN1; SMN2RORCNR1H3NR1H2RORA | |
| Bromide SCHEMBL20985051 | 0.75 | CA1 (0.52) | — | |
| SCHEMBL289673 | 0.75 | NR1H2 (0.56) | SMN1; SMN2NR1H3NR1H2MLYCD | |
| Hydrochloric Acid SCHEMBL1879313 | 0.75 | CA1 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2380879-B1 | Tetrahydroindolone and tetrahydroindazolone derivatives | ESANEX INC (US) | 2017-07-12 | — | — | EP | disclosed |