Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.31 |
| ▸ | LOX | P28300 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17666264 | 0.85 | NLRP3 (0.33) | ALDH1A1LMNAKDM4EUSP2MMP9 | |
| SCHEMBL7141142 | 0.83 | — | — | |
| SCHEMBL27046413 | 0.79 | DUT (0.39) | LOX | |
| SCHEMBL5555393 | 0.76 | — | — | |
| SCHEMBL823000 | 0.73 | — | — | |
| SCHEMBL14035740 | 0.72 | — | — | |
| SCHEMBL28923200 | 0.72 | — | — | |
| SCHEMBL223147 | 0.70 | USP2 (0.70) | ALDH1A1LMNATP53KDM4EUSP2 | |
| SCHEMBL1042519 | 0.70 | — | — | |
| SCHEMBL9284273 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3190108-A1 | HETEROCYCLIC MODULATORS OF LIPID SYNTHESIS | 3-V Biosciences, Inc. (US) | 2017-07-12 | — | — | EP | disclosed |