SCHEMBL19113752

SCHEMBL19113752

O=Nc1c(C(=O)NCC(=O)O)c(=O)n(CCC2CC2)c2cc(Oc3ccccc3)ccc12

nearest known ligand 0.79

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 20/20 0.79

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17578541 0.89 HIF1A (1.00) HIF1A
SCHEMBL19113461 0.85 HIF1A (0.69) HIF1A
SCHEMBL19113791 0.84 HIF1A (0.70) HIF1A
SCHEMBL17578427 0.79 HIF1A (1.00) HIF1A
SCHEMBL19086538 0.77 HIF1A (0.77) HIF1A
SCHEMBL23953043 0.74 HIF1A (0.79) HIF1A
SCHEMBL5308270 0.74 HIF1A (0.74) HIF1A
SCHEMBL23953026 0.73 HIF1A (0.67) HIF1A
SCHEMBL8245786 0.72 HIF1A (0.75) HIF1A
SCHEMBL17578543 0.71 HIF1A (1.00) HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3190104-A1 QUINOLINONE COMPOUND AND USE THEREOF Sunshine Lake Pharma Co., Ltd. (CN) 2017-07-12 EP disclosed