Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | ALPL | P05186 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL338266 | 0.83 | DPP4 (0.44) | GSK3BCNR1CNR2DPP4 | |
| SCHEMBL339356 | 0.82 | GSK3B (0.43) | GSK3BCNR1CNR2ALPLDPP4 | |
| SCHEMBL1911503 | 0.79 | EGLN2 (0.40) | GSK3BDPP4EGLN2 | |
| SCHEMBL1911506 | 0.77 | EGLN2 (0.41) | GSK3BDPP4EGLN2 | |
| SCHEMBL8224818 | 0.71 | EGLN2 (0.40) | GSK3BDPP4EGLN2 | |
| SCHEMBL339163 | 0.71 | DPP4 (0.44) | GSK3BDPP4 | |
| SCHEMBL340317 | 0.70 | DPP4 (0.46) | GSK3BDPP4EGLN2 | |
| SCHEMBL339648 | 0.69 | DPP4 (0.44) | GSK3BDPP4 | |
| SCHEMBL338893 | 0.69 | DPP4 (0.41) | GSK3BALPLDPP4 | |
| SCHEMBL868860 | 0.68 | DPP4 (0.43) | GSK3BDPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120077787-A1 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2012-03-29 | — | — | US | disclosed |
| US-8097617-B2 | Organic compounds | NOVARTIS AG (CH) | 2012-01-17 | — | — | US | disclosed |
| US-20090253689-A1 | Organic Compounds | NOVARTIS AG (CH) | 2009-10-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120077787-A1 | ORGANIC COMPOUNDS | OAT, GPR119, OTC | GSK3B 2067/4885CNR1 1923/4885CNR2 2213/4885 |
| US-20090253689-A1 | Organic Compounds | OAT, GPR119, OTC | GSK3B 2067/4885CNR1 1923/4885CNR2 2213/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.