Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | FLT3 | P36888 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | LIG1 | P18858 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | THRA | P10827 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11822756 | 0.83 | GAA (0.51) | TSHRGAANPC1RAB9AKDM4E | |
| SCHEMBL11821446 | 0.83 | GAA (0.62) | TSHRGAANPC1RAB9AKDM4E | |
| SCHEMBL5575328 | 0.81 | GAA (0.78) | TSHRGAANPC1RAB9AKDM4E | |
| SCHEMBL11827857 | 0.81 | GAA (0.64) | TSHRGAANPC1RAB9AKDM4E | |
| SCHEMBL7272605 | 0.81 | GAA (0.59) | TSHRGAANPC1RAB9AKDM4E | |
| SCHEMBL29389586 | 0.79 | TSHR (0.49) | TSHRGAANPC1RAB9AKDM4E | |
| SCHEMBL11823375 | 0.79 | TSHR (0.49) | TSHRGAANPC1RAB9AKDM4E | |
| SCHEMBL5575323 | 0.79 | GAA (0.61) | TSHRGAANPC1RAB9AKDM4E | |
| Hydrochloric Acid SCHEMBL11826513 | 0.78 | TSHR (0.48) | TSHRGAANPC1RAB9AKDM4E | |
| SCHEMBL11837001 | 0.76 | GAA (0.60) | TSHRGAANPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017119700-A1 | C-GLUCOSIDE DERIVATIVE CONTAINING FUSED PHENYL RING OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, PROCESS FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | 제일약품주식회사 | 2017-07-13 | — | — | WO | disclosed |