SCHEMBL29389586

SCHEMBL29389586

C=CCOc1cc(Cl)ccc1C(=O)CCN1CCCCC1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TSHR P16473 2/20 0.49
▸ GAA P10253 1/20 0.49
▸ KDM4E B2RXH2 1/20 0.44
▸ NPC1 O15118 1/20 0.44
▸ RAB9A P51151 1/20 0.44
▸ SMN1; SMN2 Q16637 1/20 0.44
▸ ALDH1A1 P00352 3/20 0.44
▸ LMNA P02545 3/20 0.44
▸ TP53 P04637 2/20 0.44
▸ HPGD P15428 1/20 0.44
▸ L3MBTL1 Q9Y468 1/20 0.44
▸ KMT2A Q03164 2/20 0.43
▸ USP2 O75604 1/20 0.43
▸ MAPT P10636 1/20 0.43
▸ HTT P42858 1/20 0.43
▸ HSD17B10 Q99714 1/20 0.43
▸ MEN1 O00255 1/20 0.43
▸ HRH3 Q9Y5N1 7/20 0.42
▸ CYP1A2 P05177 1/20 0.42
▸ CHRM2 P08172 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11823375 1.00 TSHR (0.49) TSHRGAAKDM4ENPC1RAB9A
Hydrochloric Acid SCHEMBL11826513 0.99 TSHR (0.48) TSHRGAAKDM4ENPC1RAB9A
SCHEMBL29358295 0.84 KDM4E (0.52) TSHRGAAKDM4EALDH1A1LMNA
SCHEMBL30485743 0.82 ALDH1A1 (0.52) TSHRGAAKDM4ESMN1; SMN2ALDH1A1
SCHEMBL19124093 0.79 TSHR (0.57) TSHRGAAKDM4ENPC1RAB9A
SCHEMBL9172859 0.75 LMNA (0.58) GAAKDM4EALDH1A1LMNAKMT2A
SCHEMBL5575328 0.75 GAA (0.78) TSHRGAAKDM4ENPC1RAB9A
SCHEMBL11827857 0.75 GAA (0.64) TSHRGAAKDM4ENPC1RAB9A
SCHEMBL29833947 0.74 CNR1 (0.47) TSHRGAAALDH1A1LMNAKMT2A
Hydrochloric Acid SCHEMBL11035003 0.74 LMNA (0.57) TSHRGAAKDM4EALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 126 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4376952-A1 ANTI-SIRP-ALPHA ANTIBODIES AND METHODS OF USE THEREOF Alector LLC (US) 2024-06-05 — — EP claimed
CN-114259469-B Sialic acid assisted delivery pharmaceutical composition capable of reversing tumor-related immunosenescence and preparation method and application thereof 沈阳药科大学 2023-02-21 — — CN claimed
WO-2023010076-A1 ANTI-SIRP-ALPHA ANTIBODIES AND METHODS OF USE THEREOF ALECTOR LLC (US) 2023-02-02 — — WO claimed
CN-111973570-B Sialic acid derivative modified ibrutinib nano-composite and preparation method thereof 沈阳药科大学 2022-11-25 — — CN claimed
CN-114259469-A Sialic acid assisted delivery pharmaceutical composition capable of reversing tumor-related immunosenescence and preparation method and application thereof 沈阳药科大学 2022-04-01 — — CN claimed
US-12624290-B2 Method for reducing white flicker MERCK PATENT GMBH (DE) 2026-05-12 — — US disclosed
US-12618007-B2 Liquid-crystalline medium MERCK PATENT GMBH (DE) 2026-05-05 — — US disclosed
US-20260116911-A1 NEUROACTIVE STEROIDS, COMPOSITIONS, AND USES THEREOF SAGE THERAPEUTICS INC (US) 2026-04-30 — — US disclosed
US-20260116912-A1 NEUROACTIVE STEROIDS, COMPOSITIONS, AND USES THEREOF SAGE THERAPEUTICS INC (US) 2026-04-30 — — US disclosed
EP-4733370-A1 LIQUID-CRYSTAL MEDIUM Merck Patent GmbH (DE) 2026-04-29 — — EP disclosed
US-12560413-B2 Device, system, and method of aircraft protection and countermeasures against missiles BIRD AEROSYSTEMS LTD. (IL) 2026-02-24 — — US disclosed
US-12552991-B2 Liquid-crystalline medium MERCK PATENT GMBH (DE) 2026-02-17 — — US disclosed
US-20220112426-A1 LIQUID-CRYSTAL MEDIUM MERCK PATENT GMBH (DE) 2022-04-14 — — US disclosed
EP-3978575-A1 ANTIFOULING COATING COMPOSITION Nitto Kasei Co., Ltd. (JP) 2022-04-06 — — EP disclosed
CN-114259469-A Sialic acid assisted delivery pharmaceutical composition capable of reversing tumor-related immunosenescence and preparation method and application thereof 沈阳药科大学 2022-04-01 — — CN disclosed
CN-114269863-A Antifouling coating composition 日东化成株式会社 2022-04-01 — — CN disclosed
CN-110577557-B Sialic acid lipid derivative and preparation method and application thereof 沈阳药科大学 2022-03-11 — — CN disclosed
US-11261211-B2 19-NOR neuroactive steroids and methods of use thereof SAGE THERAPEUTICS, INC. (US) 2022-03-01 — — US disclosed
US-11254872-B2 Liquid crystal media comprising polymerisable compounds MERCK PATENT GMBH (DE) 2022-02-22 — — US disclosed
CN-111057672-B Recombinant strain and application thereof 宜昌东阳光生化制药有限公司 2022-02-15 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12552991-B2 Liquid-crystalline medium FES, VIM, INHA TSHR 221/4885GAA 3771/4885KDM4E 2896/4885
US-12618007-B2 Liquid-crystalline medium SOST, NES, VIM TSHR 174/4885GAA 2472/4885KDM4E 4175/4885
US-20260116912-A1 NEUROACTIVE STEROIDS, COMPOSITIONS, AND USES THEREOF SCN4A, CHRNA4, CACNG4 TSHR 764/4885GAA 4764/4885KDM4E 1481/4885
US-20260116911-A1 NEUROACTIVE STEROIDS, COMPOSITIONS, AND USES THEREOF SCN4A, CACNG4, SLC6A4 TSHR 810/4885GAA 4679/4885KDM4E 1522/4885
US-12624290-B2 Method for reducing white flicker HCN4, HCN2, HCN3 TSHR 2060/4885GAA 4869/4885KDM4E 2158/4885
US-11261211-B2 19-NOR neuroactive steroids and methods of use thereof NR3C2, HSD3B1, NR3C1 TSHR 856/4885GAA 3951/4885KDM4E 3171/4885
US-12560413-B2 Device, system, and method of aircraft protection and countermeasures against missiles MRE11, SAMM50, LBR TSHR 854/4885GAA 3825/4885KDM4E 4400/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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