Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29389586 | 1.00 | TSHR (0.49) | TSHRGAAKDM4ENPC1RAB9A | |
| Hydrochloric Acid SCHEMBL11826513 | 0.99 | TSHR (0.48) | TSHRGAAKDM4ENPC1RAB9A | |
| SCHEMBL29358295 | 0.84 | KDM4E (0.52) | TSHRGAAKDM4EALDH1A1LMNA | |
| SCHEMBL30485743 | 0.82 | ALDH1A1 (0.52) | TSHRGAAKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL19124093 | 0.79 | TSHR (0.57) | TSHRGAAKDM4ENPC1RAB9A | |
| SCHEMBL9172859 | 0.75 | LMNA (0.58) | GAAKDM4EALDH1A1LMNAKMT2A | |
| SCHEMBL5575328 | 0.75 | GAA (0.78) | TSHRGAAKDM4ENPC1RAB9A | |
| SCHEMBL11827857 | 0.75 | GAA (0.64) | TSHRGAAKDM4ENPC1RAB9A | |
| SCHEMBL29833947 | 0.74 | CNR1 (0.47) | TSHRGAAALDH1A1LMNAKMT2A | |
| Hydrochloric Acid SCHEMBL11035003 | 0.74 | LMNA (0.57) | TSHRGAAKDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3933918-A | ANTITUSSIVE | KYOWA HAKKO KOGYO CO., LTD. (JA) | 1976-01-20 | — | — | US | disclosed |
| US-3933918-A | ANTITUSSIVE | KYOWA HAKKO KOGYO CO., LTD. (JA) | 1976-01-20 | — | — | US | disclosed |