Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 9/20 | 0.71 |
| ▸ | MAOB | P27338 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | AGXT | P21549 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7138354 | 0.83 | LTA4H (1.00) | LTA4HL3MBTL1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL12811446 | 0.83 | MAOB (0.71) | LTA4HMAOBL3MBTL1CYP1A2CYP2C19 | |
| SCHEMBL10607135 | 0.81 | LTA4H (0.67) | LTA4HMAOBL3MBTL1CALM1CYP1A2 | |
| SCHEMBL609214 | 0.81 | — | — | |
| Hydrochloric Acid SCHEMBL7435342 | 0.80 | LTA4H (0.79) | LTA4HMAOBL3MBTL1CYP1A2CYP2D6 | |
| SCHEMBL10599543 | 0.80 | LMNA (0.69) | LTA4HMAOBL3MBTL1CYP1A2CYP2C19 | |
| SCHEMBL8672820 | 0.80 | LTA4H (0.74) | LTA4HL3MBTL1CALM1CYP1A2CYP2D6 | |
| SCHEMBL11856925 | 0.80 | LMNA (0.69) | LTA4HMAOBL3MBTL1CYP1A2CYP2C19 | |
| SCHEMBL28218232 | 0.79 | TAAR1 (0.61) | LTA4HMAOBAGXT | |
| SCHEMBL10062561 | 0.78 | LTA4H (0.63) | LTA4HL3MBTL1CALM1CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1565452-B1 | 3-SUBSTITUTED-6-ARYL PYRIDINES AS LIGANDS OF C5A RECEPTORS | NOVARTIS INT PHARM LTD (BM) | 2012-04-04 | — | — | EP | disclosed |