Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.47 |
| ▸ | NPC1 | O15118 | 7/20 | 0.47 |
| ▸ | RAB9A | P51151 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | GLS | O94925 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12595552 | 0.81 | GLS (0.46) | SMN1; SMN2NPC1RAB9AALDH1A1TP53 | |
| SCHEMBL12595539 | 0.79 | MAPT (0.54) | SMN1; SMN2NPC1RAB9AALDH1A1TP53 | |
| SCHEMBL12595538 | 0.77 | GLS (0.40) | SMN1; SMN2NPC1RAB9AALDH1A1TP53 | |
| SCHEMBL12595555 | 0.77 | NPC1 (0.37) | SMN1; SMN2NPC1RAB9AALDH1A1TP53 | |
| SCHEMBL12595553 | 0.73 | NPC1 (0.35) | SMN1; SMN2NPC1RAB9AALDH1A1TP53 | |
| SCHEMBL11013247 | 0.66 | NPC1 (0.50) | SMN1; SMN2NPC1RAB9AALDH1A1TP53 | |
| SCHEMBL15748892 | 0.65 | MAPT (0.54) | SMN1; SMN2NPC1RAB9AALDH1A1MEN1 | |
| SCHEMBL20340816 | 0.64 | GSK3B (0.53) | SMN1; SMN2NPC1RAB9AALDH1A1MEN1 | |
| SCHEMBL12866599 | 0.63 | LMNA (0.41) | SMN1; SMN2NPC1RAB9AALDH1A1TP53 | |
| SCHEMBL10855864 | 0.63 | IDO1 (0.47) | SMN1; SMN2NPC1RAB9AALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170204091-A1 | TRICYCLIC SPACER SYSTEMS FOR NONLINEAR DEVICES | LIGHTWAVE LOGIC INC (US) | 2017-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170204091-A1 | TRICYCLIC SPACER SYSTEMS FOR NONLINEAR DEVICES | CCND3, CCNY, CCND2 | SMN1; SMN2 4453/4885NPC1 2641/4885RAB9A 4274/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.