Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.69 |
| ▸ | LMNA | P02545 | 1/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.69 |
| ▸ | CA12 | O43570 | 2/20 | 0.68 |
| ▸ | CA1 | P00915 | 2/20 | 0.68 |
| ▸ | CA2 | P00918 | 2/20 | 0.68 |
| ▸ | CA9 | Q16790 | 2/20 | 0.68 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.68 |
| ▸ | POLB | P06746 | 1/20 | 0.68 |
| ▸ | GAA | P10253 | 1/20 | 0.68 |
| ▸ | MAPT | P10636 | 1/20 | 0.68 |
| ▸ | CA4 | P22748 | 1/20 | 0.68 |
| ▸ | CA6 | P23280 | 1/20 | 0.68 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.68 |
| ▸ | CA7 | P43166 | 1/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.68 |
| ▸ | ERN1 | O75460 | 2/20 | 0.65 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.61 |
| ▸ | APP | P05067 | 2/20 | 0.61 |
| ▸ | PPM1B | O75688 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Terephthalic Acid SCHEMBL27943509 | 0.84 | CA12 (0.95) | KDM4ELMNAHSD17B10CA12CA1 | |
| SCHEMBL27245957 | 0.83 | ACMSD (0.75) | KDM4ELMNAHSD17B10CA12CA1 | |
| SCHEMBL31070130 | 0.83 | ACMSD (0.75) | KDM4ELMNAHSD17B10CA12CA1 | |
| SCHEMBL28364476 | 0.83 | ACMSD (0.75) | KDM4ELMNAHSD17B10CA12CA1 | |
| SCHEMBL4336129 | 0.82 | KDM4E (0.66) | KDM4ELMNAHSD17B10CA12CA1 | |
| SCHEMBL28668020 | 0.82 | KDM4E (0.62) | KDM4ELMNAHSD17B10CA12CA1 | |
| SCHEMBL5847624 | 0.82 | KDM4E (0.58) | KDM4ELMNAHSD17B10CA12CA1 | |
| SCHEMBL3688519 | 0.82 | KDM4E (0.62) | KDM4ELMNAHSD17B10CA12CA1 | |
| SCHEMBL9437164 | 0.82 | KDM4E (1.00) | KDM4ELMNAHSD17B10CA12CA1 | |
| SCHEMBL2404415 | 0.82 | HSD17B10 (0.65) | KDM4ELMNAHSD17B10CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2818531-B1 | Polymerisable compounds and the use thereof in liquid-crystal displays | MERCK PATENT GMBH (DE) | 2017-07-26 | — | — | EP | disclosed |