Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.50 |
| ▸ | CES2 | O00748 | 3/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.41 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.41 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.41 |
| ▸ | DGKA | P23743 | 1/20 | 0.41 |
| ▸ | EP300 | Q09472 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17139819 | 0.98 | NAAA (0.47) | NAAACES2EPHX1TSHRLPAR3 | |
| SCHEMBL27385831 | 0.82 | NAAA (0.48) | NAAACES2EPHX1TSHRLPAR3 | |
| SCHEMBL27276996 | 0.75 | CNR2 (0.46) | CES2TSHRDGKACES1 | |
| SCHEMBL7777442 | 0.75 | CNR2 (0.46) | CES2TSHRDGKACES1 | |
| SCHEMBL17331211 | 0.75 | CNR2 (0.46) | CES2TSHRDGKACES1 | |
| SCHEMBL15703356 | 0.75 | CNR2 (0.46) | CES2TSHRDGKACES1 | |
| SCHEMBL4736351 | 0.75 | CNR2 (0.46) | CES2TSHRDGKACES1 | |
| SCHEMBL8388930 | 0.75 | CNR2 (0.46) | CES2TSHRDGKACES1 | |
| SCHEMBL27745285 | 0.75 | CNR2 (0.46) | CES2TSHRDGKACES1 | |
| SCHEMBL28424852 | 0.72 | CES2 (0.50) | CES2TSHRDGKACES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11510988-B2 | Targeting aminoacid lipids | MERCK PATENT GMBH (DE) | 2022-11-29 | — | — | US | disclosed |
| EP-2825156-B1 | TARGETING AMINOACID LIPIDS | MERCK PATENT GMBH (DE) | 2017-07-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11510988-B2 | Targeting aminoacid lipids | PTDSS2, DNPEP, FABP1 | NAAA 243/4885CES2 1847/4885EPHX1 398/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.