Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 6/20 | 0.65 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.65 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.65 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.65 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.65 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.40 |
| ▸ | PNP | P00491 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6899968 | 0.86 | MTOR (0.76) | MTORPIK3CAPIK3CBPIK3CGPIK3C3 | |
| SCHEMBL6898844 | 0.85 | MTOR (0.69) | MTORPIK3CAPIK3CBPIK3CGPIK3C3 | |
| SCHEMBL7953012 | 0.84 | PIK3CA (0.52) | MTORPIK3CAPIK3CBPIK3CGPIK3C3 | |
| SCHEMBL6898690 | 0.83 | MTOR (0.69) | MTORPIK3CAPIK3CBPIK3CGPIK3C3 | |
| SCHEMBL6899131 | 0.82 | PIK3CA (0.65) | MTORPIK3CAPIK3CBPIK3CGPIK3C3 | |
| SCHEMBL1913668 | 0.79 | MTOR (0.80) | MTORPIK3CAPIK3CBPIK3CGPIK3C3 | |
| SCHEMBL30874351 | 0.79 | MTOR (1.00) | MTORPIK3CAPIK3CBPIK3CGPIK3C3 | |
| SCHEMBL1913379 | 0.79 | MTOR (1.00) | MTORPIK3CAPIK3CBPIK3CGPIK3C3 | |
| SCHEMBL6898715 | 0.78 | MTOR (0.67) | MTORPIK3CAPIK3CBPIK3CGPIK3C3 | |
| SCHEMBL1913389 | 0.78 | YTHDC1 (0.54) | ADORA2AADORA1HRH4PNPPDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011078795-A1 | BRIDGED MORPHOLINO SUBSTITUTED PURINES | S*BIO PTE LTD (SG) | 2011-06-30 | — | — | WO | disclosed |
| WO-2011078795-A1 | BRIDGED MORPHOLINO SUBSTITUTED PURINES | S*BIO PTE LTD (SG) | 2011-06-30 | — | — | WO | disclosed |