Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 11/20 | 0.65 |
| ▸ | MTOR | P42345 | 9/20 | 0.65 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.65 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.65 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.65 |
| ▸ | PIK3R1 | P27986 | 6/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.34 |
| ▸ | RICTOR | Q6R327 | 1/20 | 0.32 |
| ▸ | RPTOR | Q8N122 | 1/20 | 0.32 |
| ▸ | MAPKAP1 | Q9BPZ7 | 1/20 | 0.32 |
| ▸ | MLST8 | Q9BVC4 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | CDK9 | P50750 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.32 |
| ▸ | FEN1 | P39748 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6898844 | 0.87 | MTOR (0.69) | PIK3CAMTORPIK3CBPIK3CGPIK3C3 | |
| SCHEMBL6899968 | 0.86 | MTOR (0.76) | PIK3CAMTORPIK3CBPIK3CGPIK3C3 | |
| SCHEMBL6898690 | 0.85 | MTOR (0.69) | PIK3CAMTORPIK3CBPIK3CGPIK3C3 | |
| SCHEMBL6900336 | 0.83 | MTOR (0.66) | PIK3CAMTORPIK3CBPIK3CGPIK3C3 | |
| SCHEMBL6898715 | 0.82 | MTOR (0.67) | PIK3CAMTORPIK3CBPIK3CGPIK3C3 | |
| SCHEMBL1913482 | 0.82 | MTOR (0.65) | PIK3CAMTORPIK3CBPIK3CGPIK3C3 | |
| SCHEMBL6898688 | 0.80 | MTOR (0.67) | PIK3CAMTORPIK3CBPIK3CGPIK3C3 | |
| SCHEMBL1913668 | 0.79 | MTOR (0.80) | PIK3CAMTORPIK3CBPIK3CGPIK3C3 | |
| SCHEMBL6898576 | 0.79 | MTOR (0.74) | PIK3CAMTORPIK3CBPIK3CGPIK3C3 | |
| SCHEMBL6899723 | 0.79 | MTOR (0.66) | PIK3CAMTORPIK3CBPIK3CGPIK3C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011078795-A1 | BRIDGED MORPHOLINO SUBSTITUTED PURINES | S*BIO PTE LTD (SG) | 2011-06-30 | — | — | WO | disclosed |