SCHEMBL191350

SCHEMBL191350

c1csc(SSc2nccs2)n1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
FBP1 P09467 15/20 1.00
PDK1 Q15118 1/20 1.00
HTR7 P34969 1/20 0.48
FDPS P14324 1/20 0.48
ALDH1A1 P00352 2/20 0.46
TSHR P16473 1/20 0.46
NOS1 P29475 1/20 0.46
HSD17B10 Q99714 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28079135 0.89 FBP1 (0.80) FBP1PDK1HTR7FDPSALDH1A1
SCHEMBL11829207 0.88 FBP1 (0.81) FBP1PDK1HTR7FDPSALDH1A1
SCHEMBL11824120 0.88 FBP1 (0.77) FBP1PDK1HTR7FDPSALDH1A1
SCHEMBL28382830 0.87 FBP1 (0.76) FBP1PDK1HTR7FDPSALDH1A1
SCHEMBL8371244 0.85
SCHEMBL11445382 0.85
SCHEMBL9731968 0.85
SCHEMBL11818034 0.83 FBP1 (0.70) FBP1PDK1HTR7FDPSALDH1A1
SCHEMBL11819066 0.83 FBP1 (0.70) FBP1PDK1HTR7FDPSALDH1A1
SCHEMBL11824652 0.82 FBP1 (0.73) FBP1PDK1HTR7FDPS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 158 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3789447-B1 CROSSLINKING AGENTS FOR POLYMERIC SYSTEMS HENKEL AG & CO KGAA (DE) 2025-09-03 EP claimed
CN-114341260-B Cross-linking agents for polymer systems 汉高股份有限及两合公司 2024-11-19 CN claimed
US-20220162401-A1 CROSSLINKING AGENTS FOR POLYMERIC SYSTEMS HENKEL AG & CO KGAA (DE) 2022-05-26 US claimed
CN-114341260-A Crosslinking agents for polymer systems 汉高股份有限及两合公司 2022-04-12 CN claimed
WO-2021043800-A1 CROSSLINKING AGENTS FOR POLYMERIC SYSTEMS HENKEL AG & CO. KGAA (DE) 2021-03-11 WO claimed
US-10758569-B2 Heteroaryl disulfide compounds as allosteric effectors for increasing the oxygen-binding affinity of hemoglobin THE GENERAL HOSPITAL CORPORATION (US) 2020-09-01 US claimed
EP-3626707-A1 HETEROARYL DISULFIDE COMPOUNDS AS ALLOSTERIC EFFECTORS FOR INCREASING THE OXYGEN-BINDING AFFINITY OF HEMOGLOBIN The General Hospital Corporation (US) 2020-03-25 EP claimed
EP-3094619-B1 HETEROARYL DISULFIDE COMPOUNDS AS ALLOSTERIC EFFECTORS FOR INCREASING THE OXYGEN-BINDING AFFINITY OF HEMOGLOBIN MASSACHUSETTS GEN HOSPITAL (US) 2019-07-31 EP claimed
US-20160331782-A1 HETEROARYL DISULFIDE COMPOUNDS AS ALLOSTERIC EFFECTORS FOR INCREASING THE OXYGEN-BINDING AFFINITY OF HEMOGLOBIN THE GENERAL HOSPITAL CORPORATION 2016-11-17 US claimed
US-8562927-B2 Absorbent solution containing a breakdown inhibitor derived from thiazole or from oxazole and absorption process for acid compounds contained in a gaseous effluent IFP (FR) 2013-10-22 US claimed
US-20040072089-A1 Toner and process for producing toner ZEON CORPORATION (JP) 2004-04-15 US claimed
US-20030176512-A1 Asymmetric disulfides and methods of using same PROLX PHARMACEUTICALS CORPORATION (CA) 2003-09-18 US claimed
US-20030176072-A1 Polishing compositions for noble metals WANG HONGYU (US) 2003-09-18 US claimed
EP-1252248-A1 POLISHING COMPOSITIONS FOR NOBLE METALS Rodel Holdings, Inc. (US) 2002-10-30 EP claimed
US-20020111027-A1 Polishing compositions for noble metals RODEL HOLDINGS, INC. 2002-08-15 US claimed
US-20020039839-A1 Polishing compositions for noble metals RODEL HOLDINGS, INC. 2002-04-04 US claimed
WO-2001044396-A1 POLISHING COMPOSITIONS FOR NOBLE METALS RODEL HOLDINGS, INC. (US) 2001-06-21 WO claimed
EP-0247888-A1 Cross-linking halogen-containing polymers HERCULES INCORPORATED (US) 1987-12-02 EP claimed
US-4138346-A ETHOXYLATED PHOSPHATE ESTER WITH A MERCAPTOTHIAZOLE, A DITHIOBIS-THIAZOLE, A SULFIDE, A DISULFIDE OR A SULFONE BASF WYANDOTTE CORPORATION (US) 1979-02-06 US claimed
US-3933658-A PHOSPHATE ESTER AND SULFUR COMPOUND GAF CORPORATION (US) 1976-01-20 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160331782-A1 HETEROARYL DISULFIDE COMPOUNDS AS ALLOSTERIC EFFECTORS FOR INCREASING THE OXYGEN-BINDING AFFINITY OF HEMOGLOBIN HIF1AN, HBG2, HIF1A FBP1 1435/4885PDK1 1062/4885HTR7 3073/4885
US-20030176512-A1 Asymmetric disulfides and methods of using same PRDX3, PDIA5, PRDX5 FBP1 2532/4885PDK1 2344/4885HTR7 4729/4885
US-10758569-B2 Heteroaryl disulfide compounds as allosteric effectors for increasing the oxygen-binding affinity of hemoglobin HIF1AN, HBG2, HIF1A FBP1 1435/4885PDK1 1062/4885HTR7 3073/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.