PDIA5

Protein disulfide-isomerase A5 · Q14554 · PDIA5 on Sugi Atlas →

0 patent compounds predicted against PDIA5, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to PDIA5 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Effects of Liraglutide on ER Stress in Obese Patients With Type 2 Diabetes PHASE4UNKNOWN
Targeting Endoplasmic Reticulum Stress in Human Hypertension PHASE1/PHASE2RECRUITING
Ambroxol Therapy for Patients With Type 1 Gaucher Disease and Suboptimal Response to Enzyme Replacement Therapy PHASE2COMPLETED
Evaluation of the Possible Safety and Efficacy of Dapagliflozin in the Prophylaxis of Doxorubicin-Induced Cardiotoxicity PHASE2RECRUITING
Pembrolizumab Plus Enfortumab Vedotin in Collecting Duct and Renal Medullary Carcinoma PHASE2RECRUITING
Biologic Correlative Taxotere/AC PHASE2COMPLETED
Safety and Pharmacology of SNX-5422 Plus Carboplatin and Paclitaxel in Subjects With Solid Tumors PHASE1COMPLETED
Study of Oral CNF2024 (BIIB021) in Advanced Solid Tumors PHASE1COMPLETED
A Phase I Study of Pyrimethamine in Patients With GM2 Gangliosidosis PHASE1WITHDRAWN
PBA Use for Treatment of ATF6-/- Patients EARLY_PHASE1SUSPENDED
Quantification of GADD34 Expression in RA nanCOMPLETED
Thiol/Disulphide Homeostasis in Unexplained Infertility nanCOMPLETED
Establishment of Human Cellular Disease Models for Wilson Disease nanCOMPLETED
Cellular Proteome From Leukocytes of Glaucoma Patients in Comparison With Patients With Alzheimer's Disease nanWITHDRAWN
Cellular Proteome From Leukocytes of Glaucoma Patients in Comparison With Patients With Parkinson's Disease nanWITHDRAWN
Endoplasmic Reticulum Stress and Resistance to Treatments in Ph-negative Myeloproliferative Neoplasms nanCOMPLETED
Liver Fibrosis in Alpha-1 Antitrypsin Deficiency (Liver AATD) nanCOMPLETED
Effect of Protein on Endoplasmic Reticulum Stress nanNOT_YET_RECRUITING
Hereditary Spastic Paraplegia Genomic Sequencing Initiative (HSPseq) nanRECRUITING
Neutrophils as Prognostic Factors in Granulomatosis With Polyangiitis (Formerly Named Wegener's Granulomatosis) nanCOMPLETED
Pharmacogenomics of Interferon and Ribavirin Treatment in Patients With Chronic Hepatitis C Virus Infection nanUNKNOWN
MERC Proteins in Saliva and GCF in Periodontal Disease (ELISA Study) nanCOMPLETED
Efficacy of Solarplast for Health and Oxidative Stress nanCOMPLETED
Transcranial Magnetic Stimulation (TMS) Studies of Dystonia nanCOMPLETED
Proteomic Profiling to Reveal Novel Prognostic Markers for Neurological Outcome Following Resuscitation nanCOMPLETED
Registry and Natural History Study for Early Onset Hereditary Spastic Paraplegia nanRECRUITING
Proteomic Analysis of Serum Samples After Cardiac Arrest: a TTM-trial Substudy nanACTIVE_NOT_RECRUITING
Shwachman Diamond Syndrome Registry and Study nanRECRUITING
Acute Passive Heating in Healthy Older Adults nanCOMPLETED
Genetic Studies of Lysosomal Storage Disorders nanENROLLING_BY_INVITATION

Related proteins — ESM-2 sequence neighbours (a PDIA5 binder may also engage these)

ProteinNameSimilarity
Q921X9 1.000 Q921X9 →
Q5I0H9 1.000 Q5I0H9 →
Q2KIL5 1.000 Q2KIL5 →
P81628 0.988 P81628 →
TXNDC5 Thioredoxin domain-containing protein 5 0.987 landscape →
P08003 0.987 P08003 →
P38659 0.985 P38659 →
Q9DC23 0.984 Q9DC23 →
Q29RV1 0.984 Q29RV1 →
P05307 0.983 P05307 →
PDIA4 Protein disulfide-isomerase A4 0.983 landscape →
P38657 0.982 P38657 →
Q53LQ0 0.982 Q53LQ0 →
Q8GYD1 0.982 Q8GYD1 →
Q5R5B6 0.981 Q5R5B6 →
Q7XRB5 0.981 Q7XRB5 →
P09102 0.981 P09102 →
Q4VIT4 0.981 Q4VIT4 →
Q67IX6 0.981 Q67IX6 →
A0A8M1N5Y4 0.980 A0A8M1N5Y4 →
P27773 0.979 P27773 →
P21195 0.978 P21195 →
ERP29 Endoplasmic reticulum resident protein 29 0.978 landscape →
Q91W90 0.978 Q91W90 →
Q17688 0.978 Q17688 →
P11598 0.978 P11598 →
Q9VYV3 0.978 Q9VYV3 →
Q66GQ3 0.978 Q66GQ3 →
D3Z6P0 0.978 D3Z6P0 →
Q5RDG4 0.977 Q5RDG4 →