Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19135609 | 0.89 | GPR84 (0.31) | GPR84PDE4A | |
| SCHEMBL19135647 | 0.88 | GRM5 (0.31) | GPR84GRM5PDE4A | |
| SCHEMBL19135691 | 0.87 | GPR84 (0.32) | GPR84GRM5PDE4A | |
| SCHEMBL15900849 | 0.82 | GPR84 (0.46) | GPR84GRM5PDE4A | |
| SCHEMBL15901268 | 0.80 | GPR84 (0.38) | GPR84GRM5PDE4A | |
| SCHEMBL19135640 | 0.79 | P2RX7 (0.33) | GPR84PDE4A | |
| SCHEMBL19135646 | 0.74 | GPR84 (0.44) | GPR84PDE4A | |
| SCHEMBL19135649 | 0.74 | P2RX7 (0.31) | GPR84 | |
| SCHEMBL15901284 | 0.72 | GPR84 (0.35) | GPR84GRM5PDE4A | |
| SCHEMBL15900767 | 0.70 | GPR84 (0.46) | GPR84GRM5PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9708330-B2 | 2,3-dihydroimidazol[1,2-C]pyrimidin-5(1-H)-one based ipoprotein-associated phospholipase A2 (Lp-PLA2) inhibitors | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2017-07-18 | — | — | US | disclosed |