Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 13/20 | 0.48 |
| ▸ | CDK5 | Q00535 | 10/20 | 0.48 |
| ▸ | CDK5R1 | Q15078 | 10/20 | 0.48 |
| ▸ | CCNA2 | P20248 | 10/20 | 0.48 |
| ▸ | CCNA1 | P78396 | 10/20 | 0.48 |
| ▸ | DYRK1A | Q13627 | 8/20 | 0.48 |
| ▸ | CDK1 | P06493 | 6/20 | 0.47 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.47 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.47 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.45 |
| ▸ | MTOR | P42345 | 2/20 | 0.45 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.45 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.45 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | PI4KA | P42356 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1578570 | 0.88 | PIK3CA (0.49) | CDK2CDK5CDK5R1CCNA2CCNA1 | |
| SCHEMBL1913382 | 0.86 | PIK3CA (0.60) | CDK2CDK5CDK5R1CCNA2CCNA1 | |
| SCHEMBL539257 | 0.80 | PIK3CA (0.62) | CDK2CDK5CDK5R1CCNA2CCNA1 | |
| SCHEMBL1913604 | 0.78 | MTOR (0.42) | CDK2CDK5CDK5R1CCNA2CCNA1 | |
| SCHEMBL3441256 | 0.77 | CDK2 (0.71) | CDK2CDK5CDK5R1CCNA2CCNA1 | |
| SCHEMBL28712236 | 0.76 | CDK2 (0.49) | CDK2CDK5CDK5R1CCNA2CCNA1 | |
| SCHEMBL1913389 | 0.74 | YTHDC1 (0.54) | CDK1ADORA2AADORA1PI4KAPI4K2B | |
| SCHEMBL1913668 | 0.74 | MTOR (0.80) | CDK2CDK5CCNA2CCNA1CDK1 | |
| SCHEMBL22587405 | 0.74 | CDK1 (0.58) | CDK2CDK5CDK5R1CCNA2CCNA1 | |
| SCHEMBL539356 | 0.74 | CDK2 (0.56) | CDK2CDK5CDK5R1CCNA2CCNA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011078795-A1 | BRIDGED MORPHOLINO SUBSTITUTED PURINES | S*BIO PTE LTD (SG) | 2011-06-30 | — | — | WO | disclosed |
| WO-2011078795-A1 | BRIDGED MORPHOLINO SUBSTITUTED PURINES | S*BIO PTE LTD (SG) | 2011-06-30 | — | — | WO | disclosed |