Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | ATM | Q13315 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | CTSB | P07858 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18171808 | 0.90 | MAPT (0.60) | ALDH1A1ATMMAPTL3MBTL1TDP1 | |
| SCHEMBL26239298 | 0.88 | ALDH1A1 (0.58) | ALDH1A1ATMMAPTL3MBTL1TDP1 | |
| SCHEMBL29587852 | 0.88 | ALDH1A1 (0.58) | ALDH1A1ATMMAPTL3MBTL1TDP1 | |
| SCHEMBL15080869 | 0.88 | CTSK (0.61) | ATMCTSB | |
| SCHEMBL30946598 | 0.88 | CTSK (0.61) | ATMCTSB | |
| SCHEMBL6897142 | 0.87 | CTSK (0.54) | ATMCTSB | |
| SCHEMBL23056471 | 0.87 | MAPT (0.54) | ALDH1A1ATMMAPTL3MBTL1TDP1 | |
| SCHEMBL22692566 | 0.86 | ALDH1A1 (0.58) | ALDH1A1ATMMAPTL3MBTL1TDP1 | |
| SCHEMBL10099537 | 0.85 | GAA (0.52) | ALDH1A1ATMMAPTL3MBTL1TDP1 | |
| SCHEMBL29233276 | 0.85 | ATM (0.51) | ALDH1A1ATMMAPTL3MBTL1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011069149-A2 | CATHEPSIN S INHIBITORS | DCB-USA LLC (US) | 2011-06-09 | — | — | WO | disclosed |