SCHEMBL191379

SCHEMBL191379

C/C=C/CC1CC2C=CC1C2

nearest known ligand 0.43

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 7/20 0.43
ALDH1A1 P00352 3/20 0.43
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
HTT P42858 1/20 0.36
TSHR P16473 1/20 0.35
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL191380 1.00 KDM4E (0.43) KDM4EALDH1A1MEN1KMT2AHTT
SCHEMBL28736283 0.88 KDM4E (0.36) KDM4EALDH1A1MEN1KMT2AHTT
SCHEMBL19467704 0.81 KDM4E (0.41) KDM4EALDH1A1MEN1KMT2AHTT
SCHEMBL11330514 0.80 KDM4E (0.40) KDM4EALDH1A1MEN1KMT2AHTT
SCHEMBL9644755 0.79 KDM4E (0.44) KDM4EALDH1A1MEN1KMT2AHTT
SCHEMBL136620 0.77 KDM4E (0.38) KDM4EALDH1A1MEN1KMT2AHTT
SCHEMBL136619 0.77 KDM4E (0.38) KDM4EALDH1A1MEN1KMT2AHTT
SCHEMBL8038765 0.75 KDM4E (0.37) KDM4EALDH1A1MEN1KMT2AHTT
SCHEMBL8038766 0.75 KDM4E (0.37) KDM4EALDH1A1MEN1KMT2AHTT
SCHEMBL13346475 0.75 KDM4E (0.37) KDM4EALDH1A1MEN1KMT2AHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240150566-A1 HEAT-RESISTANT EPDM COMPOSITION, AND ASSOCIATED FORMULATION METHOD AND PARTS THE TORONTO-DOMINION BANK, AS AGENT (CA) 2024-05-09 US claimed
WO-2024047583-A1 PREPARATION OF SILANE-GRAFTED EPDM AND MOISTURE CURING THEREOF AIRBOSS OF AMERICA CORP. (CA) 2024-03-07 WO claimed
EP-4305102-A1 HEAT-RESISTANT EPDM COMPOSITION, AND ASSOCIATED FORMULATION METHOD AND PARTS Airboss of America Corp. (CA) 2024-01-17 EP claimed
EP-3197881-B1 DIAZIRINE COMPOUNDS AS PHOTOCROSSLINKERS AND PHOTOIMAGEABLE COMPOSITIONS COMPRISING THEM PROMERUS LLC (US) 2020-04-29 EP claimed
US-10303060-B2 Diazirine compounds and compositions derived therefrom PROMERUS, LLC (US) 2019-05-28 US claimed
US-20180186747-A1 DIAZIRINE COMPOUNDS AND COMPOSITIONS DERIVED THEREFROM PROMERUS, LLC (US) 2018-07-05 US claimed
US-9938241-B2 Diazirine compounds and compositions derived therefrom PROMERUS, LLC (US) 2018-04-10 US claimed
US-20160147145-A1 PHOTOIMAGEABLE COMPOSITIONS CONTAINING OXETANE FUNCTIONALITY PROMERUS, LLC 2016-05-26 US claimed
US-20160083352-A1 DIAZIRINE COMPOUNDS AND COMPOSITIONS DERIVED THEREFROM SUMITOMO BAKELITE CO., LTD. (JP) 2016-03-24 US claimed
EP-0298408-B1 METHOD FOR PREPARING NORBORNENE STRUCTURE COMPOUND NIPPON OIL CO. LTD. (JP) 1991-12-18 EP claimed
US-4017669-A COORDINATION CATALYST E. I. DU PONT DE NEMOURS AND COMPANY (US) 1977-04-12 US claimed
EP-4695332-A1 RUBBER COMPOSITION, AND ASSOCIATED FORMULATION METHOD AND PARTS Airboss of America Corp. (CA) 2026-02-18 EP disclosed
EP-4581064-A1 PREPARATION OF SILANE-GRAFTED EPDM AND MOISTURE CURING THEREOF Airboss of America Corp. (CA) 2025-07-09 EP disclosed
WO-2024214043-A1 RUBBER COMPOSITION, AND ASSOCIATED FORMULATION METHOD AND PARTS AIRBOSS OF AMERICA CORP. (CA) 2024-10-17 WO disclosed
US-20240150566-A1 HEAT-RESISTANT EPDM COMPOSITION, AND ASSOCIATED FORMULATION METHOD AND PARTS THE TORONTO-DOMINION BANK, AS AGENT (CA) 2024-05-09 US disclosed
US-4770782-A Method for preventing gel/emulsion formation EXXON CHEMICAL PATENTS INC. (US) 1988-09-13 US disclosed
EP-0202060-A1 Use of silicate as chain branching suppressor in EPDM production EXXON CHEMICAL PATENTS INC. (US) 1986-11-20 EP disclosed
US-4093583-A WITH AN ALPHA-OLEFIN AND A NONCONJUGATED DIENE, CURING AGENT, ACTIVATOR E. I. DU PONT DE NEMOURS AND COMPANY (US) 1978-06-06 US disclosed
US-4017669-A COORDINATION CATALYST E. I. DU PONT DE NEMOURS AND COMPANY (US) 1977-04-12 US disclosed
US-4016349-A SOLVENT EXTRACTION, SOLID SUPPORT E. I. DU PONT DE NEMOURS AND COMPANY (US) 1977-04-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160083352-A1 DIAZIRINE COMPOUNDS AND COMPOSITIONS DERIVED THEREFROM RDX, AOX1, ALDH1A2 KDM4E 2719/4885ALDH1A1 24/4885MEN1 3151/4885
US-20180186747-A1 DIAZIRINE COMPOUNDS AND COMPOSITIONS DERIVED THEREFROM ZYX, AOX1, RDX KDM4E 1745/4885ALDH1A1 145/4885MEN1 2280/4885
US-10303060-B2 Diazirine compounds and compositions derived therefrom ZYX, AOX1, RDX KDM4E 1745/4885ALDH1A1 145/4885MEN1 2280/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.