Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 2/20 | 0.63 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.63 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.63 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.63 |
| ▸ | HTR2B | P41595 | 1/20 | 0.63 |
| ▸ | MC3R | P41968 | 1/20 | 0.63 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.63 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.63 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.63 |
| ▸ | TBXA2R | P21731 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.52 |
| ▸ | PTGFR | P43088 | 2/20 | 0.52 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.52 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.52 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.52 |
| ▸ | SLCO2A1 | Q92959 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Unoprostone SCHEMBL194651 | 0.92 | PGR (0.73) | PGRADORA3SLC6A2ADRA2CHTR2B | |
| Unoprostone SCHEMBL18605546 | 0.92 | PGR (0.73) | PGRADORA3SLC6A2ADRA2CHTR2B | |
| Unoprostone SCHEMBL1286324 | 0.92 | PGR (0.73) | PGRADORA3SLC6A2ADRA2CHTR2B | |
| Unoprostone SCHEMBL2469329 | 0.92 | PGR (0.73) | PGRADORA3SLC6A2ADRA2CHTR2B | |
| SCHEMBL6409055 | 0.92 | PGR (0.73) | PGRADORA3SLC6A2ADRA2CHTR2B | |
| Unoprostone SCHEMBL14957866 | 0.92 | PGR (0.73) | PGRADORA3SLC6A2ADRA2CHTR2B | |
| Unoprostone SCHEMBL1286326 | 0.92 | PGR (0.73) | PGRADORA3SLC6A2ADRA2CHTR2B | |
| Unoprostone SCHEMBL2469324 | 0.92 | PGR (0.73) | PGRADORA3SLC6A2ADRA2CHTR2B | |
| Unoprostone SCHEMBL22965277 | 0.92 | PGR (0.73) | PGRADORA3SLC6A2ADRA2CHTR2B | |
| SCHEMBL6409062 | 0.92 | PGR (0.73) | PGRADORA3SLC6A2ADRA2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180050999-A1 | PROCESSES AND INTERMEDIATES FOR THE PREPARATIONS OF ISOMER FREE PROSTAGLANDINS | CHIROGATE INTERNATIONAL INC. (TW) | 2018-02-22 | — | — | US | disclosed |
| EP-2429507-B1 | PHOSPHATE-FREE PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF GLAUCOMA | URSAPHARM ARZNEIMITTEL GMBH (DE) | 2017-07-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180050999-A1 | PROCESSES AND INTERMEDIATES FOR THE PREPARATIONS OF ISOMER FREE PROSTAGLANDINS | PTGER2, PTGES2, PTGER1 | PGR 631/4885ADORA3 1200/4885SLC6A2 3615/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.