Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 2/20 | 0.73 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.73 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.73 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.73 |
| ▸ | HTR2B | P41595 | 1/20 | 0.73 |
| ▸ | MC3R | P41968 | 1/20 | 0.73 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.73 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.73 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.73 |
| ▸ | TBXA2R | P21731 | 4/20 | 0.57 |
| ▸ | PTGFR | P43088 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.57 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.57 |
| ▸ | SLCO2A1 | Q92959 | 2/20 | 0.57 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.57 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Unoprostone SCHEMBL194651 | 1.00 | PGR (0.73) | PGRADORA3SLC6A2ADRA2CHTR2B | |
| SCHEMBL6409062 | 1.00 | PGR (0.73) | PGRADORA3SLC6A2ADRA2CHTR2B | |
| Unoprostone SCHEMBL18605546 | 1.00 | PGR (0.73) | PGRADORA3SLC6A2ADRA2CHTR2B | |
| Unoprostone SCHEMBL1286324 | 1.00 | PGR (0.73) | PGRADORA3SLC6A2ADRA2CHTR2B | |
| Unoprostone SCHEMBL2469329 | 1.00 | PGR (0.73) | PGRADORA3SLC6A2ADRA2CHTR2B | |
| Unoprostone SCHEMBL14957866 | 1.00 | PGR (0.73) | PGRADORA3SLC6A2ADRA2CHTR2B | |
| SCHEMBL6409055 | 1.00 | PGR (0.73) | PGRADORA3SLC6A2ADRA2CHTR2B | |
| Unoprostone SCHEMBL1286326 | 1.00 | PGR (0.73) | PGRADORA3SLC6A2ADRA2CHTR2B | |
| Unoprostone SCHEMBL22965277 | 1.00 | PGR (0.73) | PGRADORA3SLC6A2ADRA2CHTR2B | |
| Unoprostone SCHEMBL572177 | 1.00 | PGR (0.73) | PGRADORA3SLC6A2ADRA2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230233516-A1 | HIGH PENETRATION COMPOSITIONS AND THEIR APPLICATIONS | TECHFIELDS PHARMA CO., LTD (CN) | 2023-07-27 | — | — | US | disclosed |
| US-11541029-B2 | High penetration compositions and their applications | TECHFIELDS PHARMA CO., LTD. (CN) | 2023-01-03 | — | — | US | disclosed |
| US-20130131106-A1 | BIFUNCTIONAL RHO KINASE INHIBITOR COMPOUNDS, COMPOSITION AND USE | INSPIRE PHARMACEUTICALS, INC. (US) | 2013-05-23 | — | — | US | disclosed |
| US-20110269689-A1 | HIGH PENETRATION COMPOSITIONS AND THEIR APPLICATIONS | PREMIER RESEARCH INTERNATIONAL, LLC | 2011-11-03 | — | — | US | disclosed |
| EP-2370406-A1 | HIGH PENETRATION COMPOSITIONS AND THEIR APPLICATIONS | Yu, Chongxi (US) | 2011-10-05 | — | — | EP | disclosed |
| US-7790905-B2 | Pharmaceutical propylene glycol solvate compositions | MCNEIL-PPC, INC. (US) | 2010-09-07 | — | — | US | disclosed |
| WO-2010065936-A1 | HIGH PENETRATION COMPOSITIONS AND THEIR APPLICATIONS | YU CHONGXI (US) | 2010-06-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110269689-A1 | HIGH PENETRATION COMPOSITIONS AND THEIR APPLICATIONS | SLC19A1, HIRA, SLC43A1 | PGR 996/4885ADORA3 1145/4885SLC6A2 54/4885 |
| US-11541029-B2 | High penetration compositions and their applications | SLC19A1, HIRA, SLC43A1 | PGR 996/4885ADORA3 1145/4885SLC6A2 54/4885 |
| US-20130131106-A1 | BIFUNCTIONAL RHO KINASE INHIBITOR COMPOUNDS, COMPOSITION AND USE | ROCK2, ROCK1, RHOA | PGR 4537/4885ADORA3 3954/4885SLC6A2 4368/4885 |
| US-20230233516-A1 | HIGH PENETRATION COMPOSITIONS AND THEIR APPLICATIONS | SLC5A7, SLC19A1, SLC43A1 | PGR 1262/4885ADORA3 721/4885SLC6A2 19/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.