Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB7A | P51149 | 1/20 | 0.42 |
| ▸ | KIF11 | P52732 | 2/20 | 0.41 |
| ▸ | FABP4 | P15090 | 3/20 | 0.39 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CACNA1G | O43497 | 4/20 | 0.36 |
| ▸ | CACNA1H | O95180 | 4/20 | 0.36 |
| ▸ | CACNA1I | Q9P0X4 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19141326 | 0.80 | KIF11 (0.35) | RAB7AKIF11FABP4FABP5 | |
| SCHEMBL19140926 | 0.79 | RAB7A (0.56) | RAB7AKIF11FABP4FABP5PDE4B | |
| SCHEMBL19141653 | 0.79 | RAB7A (0.47) | RAB7AKIF11FABP4FABP5PDE4B | |
| SCHEMBL19141088 | 0.78 | RAB7A (0.48) | RAB7AKIF11FABP4FABP5PDE4B | |
| SCHEMBL19140971 | 0.71 | KIF11 (0.38) | RAB7AKIF11PDE4DMAPTTP53 | |
| SCHEMBL19141360 | 0.70 | RAB7A (0.37) | RAB7AKIF11FABP4FABP5PDE4B | |
| SCHEMBL19140934 | 0.69 | RAB7A (0.42) | RAB7AKIF11FABP4FABP5PDE4B | |
| SCHEMBL19140455 | 0.68 | RAB7A (0.61) | RAB7AKIF11FABP4FABP5PDE4B | |
| SCHEMBL19321121 | 0.67 | RAB7A (0.60) | RAB7AKIF11FABP4FABP5PDE4B | |
| SCHEMBL19141234 | 0.67 | RAB7A (0.60) | RAB7AKIF11FABP4FABP5PDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3192794-A1 | SUSTAINED HIV PROTEASE INHIBITOR | Shionogi & Co., Ltd. (JP) | 2017-07-19 | — | — | EP | disclosed |