SCHEMBL989611

SCHEMBL989611

COC(=O)CCCCCCCCC(=O)Cl

nearest known ligand 0.64

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.64
ALDH1A1 P00352 3/20 0.56
LMNA P02545 2/20 0.55
TP53 P04637 1/20 0.48
KAT2B Q92831 3/20 0.46
KMT2A Q03164 2/20 0.46
RECQL P46063 1/20 0.45
EPHX2 P34913 3/20 0.44
L3MBTL1 Q9Y468 1/20 0.43
MEN1 O00255 1/20 0.41
POLB P06746 1/20 0.41
POLA1 P09884 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2527082 1.00 TSHR (0.64) TSHRALDH1A1LMNATP53KAT2B
SCHEMBL7407458 1.00 TSHR (0.64) TSHRALDH1A1LMNATP53KAT2B
SCHEMBL19141 1.00 TSHR (0.64) TSHRALDH1A1LMNATP53KAT2B
SCHEMBL4204017 1.00 TSHR (0.64) TSHRALDH1A1LMNATP53KAT2B
SCHEMBL719374 1.00 TSHR (0.64) TSHRALDH1A1LMNATP53KAT2B
SCHEMBL7408161 1.00 TSHR (0.64) TSHRALDH1A1LMNATP53KAT2B
SCHEMBL9353850 1.00 TSHR (0.64) TSHRALDH1A1LMNATP53KAT2B
SCHEMBL642929 0.98 TSHR (0.67) TSHRALDH1A1LMNATP53KAT2B
SCHEMBL48697 0.93 TSHR (0.75) TSHRALDH1A1LMNATP53KAT2B
SCHEMBL3502791 0.87 TSHR (0.82) TSHRALDH1A1LMNAKMT2ARECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 91 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1841747-B1 OXAZOLE HYDROXAMIC ACID DERIVATIVES AND USE THEREOF SK BIOPHARMACEUTICALS CO LTD (KR) 2012-09-05 EP claimed
US-20090209596-A1 Oxazole Hydroxamic Acid Derivatives and Use Thereof SK HOLDINGS CO., LTD 2009-08-20 US claimed
EP-1841747-A1 OXAZOLE HYDROXAMIC ACID DERIVATIVES AND USE THEREOF SK Corporation (KR) 2007-10-10 EP claimed
WO-2006075888-A1 OXAZOLE HYDROXAMIC ACID DERIVATIVES AND USE THEREOF SK CORPORATION (KR) 2006-07-20 WO claimed
CN-122055150-A Cyproheptadine derivatives 思凯生科股份有限公司 2026-05-15 CN disclosed
US-20260102348-A1 COMPOUND OR SALT THEREOF AND LIPID PARTICLES FUJIFILM CORPORATION (JP) 2026-04-16 US disclosed
EP-4332086-B1 COMPOUND OR SALT THEREOF, LIPID PARTICLES, AND PHARMACEUTICAL COMPOSITION FUJIFILM CORP (JP) 2026-04-08 EP disclosed
US-12508226-B2 Lipid composition FUJIFILM CORPORATION (JP) 2025-12-30 US disclosed
US-12370143-B2 Compound or salt thereof and lipid particles FUJIFILM CORPORATION (JP) 2025-07-29 US disclosed
EP-4328309-B1 LIPID COMPOSITION FUJIFILM CORP (JP) 2025-07-02 EP disclosed
US-12285525-B2 Compound or salt thereof and lipid particles FUJIFILM CORPORATION (JP) 2025-04-29 US disclosed
CN-116172975-B Lipid particle, nucleic acid drug comprising same, and composition for nucleic acid delivery 富士胶片株式会社 2025-03-28 CN disclosed
US-5338854-A Detectors for study of natural or synthetic lipid membranes MOLECULAR PROBES, INC. (US) 1994-08-16 US disclosed
US-5300672-A For water systems, plant diseases ROHM AND HAAS COMPANY (US) 1994-04-05 US disclosed
US-5250669-A Thermostability, photoresists WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 1993-10-05 US disclosed
US-5166390-A Bactericides ROHM AND HAAS COMPANY (US) 1992-11-24 US disclosed
EP-0174271-B1 ANTHRACEME DERIVATIVES CIBA-GEIGY AG (CH) 1991-10-16 EP disclosed
EP-0440329-A1 S-substituted carbonyl substituted betathioacrylamide biocides and fungicides ROHM AND HAAS COMPANY (US) 1991-08-07 EP disclosed
EP-0323050-A2 Photosensitive compound WAKO PURE CHEMICAL INDUSTRIES LTD (JP) 1989-07-05 EP disclosed
EP-0174271-A2 Anthraceme derivatives CIBA-GEIGY AG (CH) 1986-03-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12370143-B2 Compound or salt thereof and lipid particles NR1H3, NR1H2, LDLR TSHR 999/4885ALDH1A1 2243/4885LMNA 2518/4885
US-12285525-B2 Compound or salt thereof and lipid particles NR1H3, NR1H2, LDLR TSHR 999/4885ALDH1A1 2243/4885LMNA 2518/4885
US-20260102348-A1 COMPOUND OR SALT THEREOF AND LIPID PARTICLES LDLR, NR1H3, NR1H2 TSHR 1103/4885ALDH1A1 2418/4885LMNA 1252/4885
US-20090209596-A1 Oxazole Hydroxamic Acid Derivatives and Use Thereof HDAC1, HDAC5, HDAC7 TSHR 4146/4885ALDH1A1 424/4885LMNA 3307/4885
US-12508226-B2 Lipid composition APOB, NAF1, SLC27A1 TSHR 1216/4885ALDH1A1 2907/4885LMNA 1148/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.