Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | KAT2B | Q92831 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | POLA1 | P09884 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2527082 | 1.00 | TSHR (0.64) | TSHRALDH1A1LMNATP53KAT2B | |
| SCHEMBL19141 | 1.00 | TSHR (0.64) | TSHRALDH1A1LMNATP53KAT2B | |
| SCHEMBL4204017 | 1.00 | TSHR (0.64) | TSHRALDH1A1LMNATP53KAT2B | |
| SCHEMBL719374 | 1.00 | TSHR (0.64) | TSHRALDH1A1LMNATP53KAT2B | |
| SCHEMBL7408161 | 1.00 | TSHR (0.64) | TSHRALDH1A1LMNATP53KAT2B | |
| SCHEMBL989611 | 1.00 | TSHR (0.64) | TSHRALDH1A1LMNATP53KAT2B | |
| SCHEMBL9353850 | 1.00 | TSHR (0.64) | TSHRALDH1A1LMNATP53KAT2B | |
| SCHEMBL642929 | 0.98 | TSHR (0.67) | TSHRALDH1A1LMNATP53KAT2B | |
| SCHEMBL48697 | 0.93 | TSHR (0.75) | TSHRALDH1A1LMNATP53KAT2B | |
| SCHEMBL3502791 | 0.87 | TSHR (0.82) | TSHRALDH1A1LMNAKMT2ARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0031727-B1 | MEDICINAL COMPOSITIONS COMPRISING AS AN ACTIVE INGREDIENT SUBSTITUTED 1,4-BENZOQUINONES | Takeda Chemical Industries, Ltd. (JP) | 1986-07-30 | — | — | EP | disclosed |
| US-4495104-A | PHARMACEUTICAL COMPOUNDS EFFECTIVE AGAINST HEART FAILURE, DERIODONTAL DISEASE, DIABETES; HYPOTENSIVE AND ANTIANAPHYLACTIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1985-01-22 | — | — | US | disclosed |
| EP-0021841-B1 | 2,3-DIALKOXY-1,4-QUINONE DERIVATIVES; METHOD OF PRODUCING 1,4-QUINONE DERIVATIVES | Takeda Chemical Industries, Ltd. (JP) | 1984-10-24 | — | — | EP | disclosed |
| US-4436753-A | CARDIOVASCULAR DISORDERS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1984-03-13 | — | — | US | disclosed |
| EP-0031727-A2 | Medicinal compositions comprising as an active ingredient substituted 1,4-benzoquinones | Takeda Chemical Industries, Ltd. (JP) | 1981-07-08 | — | — | EP | disclosed |
| EP-0021841-A2 | 2,3-Dialkoxy-1,4-quinone derivatives; method of producing 1,4-quinone derivatives | Takeda Chemical Industries, Ltd. (JP) | 1981-01-07 | — | — | EP | disclosed |