Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14981149 | 0.81 | KCNMA1 (0.49) | SMN1; SMN2TSHRKCNMA1ALDH1A1GAA | |
| SCHEMBL4209963 | 0.78 | KCNMA1 (0.64) | SMN1; SMN2TSHRKCNMA1ALDH1A1GAA | |
| SCHEMBL26551915 | 0.77 | KCNMA1 (0.51) | SMN1; SMN2TSHRKCNMA1ALDH1A1GAA | |
| SCHEMBL25078456 | 0.74 | KCNMA1 (0.58) | SMN1; SMN2TSHRKCNMA1ALDH1A1GAA | |
| SCHEMBL12859913 | 0.73 | SMN1; SMN2 (0.57) | SMN1; SMN2TSHRKCNMA1ALDH1A1GAA | |
| SCHEMBL13604189 | 0.73 | MAPT (0.47) | SMN1; SMN2TSHRKCNMA1ALDH1A1RAB9A | |
| SCHEMBL13589297 | 0.73 | SMN1; SMN2 (0.52) | SMN1; SMN2TSHRKCNMA1ALDH1A1GAA | |
| SCHEMBL24060749 | 0.73 | KCNMA1 (0.53) | SMN1; SMN2TSHRKCNMA1ALDH1A1GAA | |
| SCHEMBL30987402 | 0.72 | KCNMA1 (0.60) | SMN1; SMN2TSHRKCNMA1ALDH1A1GAA | |
| SCHEMBL14421241 | 0.72 | KCNMA1 (0.60) | SMN1; SMN2TSHRKCNMA1ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3192789-A1 | NITROGENATED HETEROCYCLIC RING DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME | Idemitsu Kosan Co., Ltd. (JP) | 2017-07-19 | — | — | EP | disclosed |