Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | PPARD | Q03181 | 9/20 | 0.47 |
| ▸ | PPARA | Q07869 | 8/20 | 0.47 |
| ▸ | PPARG | P37231 | 4/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.41 |
| ▸ | NTSR1 | P30989 | 3/20 | 0.40 |
| ▸ | KMO | O15229 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30103437 | 0.81 | KMT2A (0.62) | KMT2APPARDPPARAPPARGITGB3 | |
| SCHEMBL4234811 | 0.81 | KMT2A (0.62) | KMT2APPARDPPARAPPARGITGB3 | |
| SCHEMBL28607801 | 0.80 | KMT2A (0.60) | KMT2APPARDPPARAPPARGITGB3 | |
| SCHEMBL1576340 | 0.80 | KMT2A (0.60) | KMT2APPARDPPARAPPARG | |
| SCHEMBL5537950 | 0.80 | KMT2A (0.60) | KMT2APPARDPPARAPPARGNTSR1 | |
| SCHEMBL418013 | 0.80 | KMT2A (0.60) | KMT2APPARDPPARAPPARGNTSR1 | |
| SCHEMBL9702533 | 0.80 | KMT2A (0.60) | KMT2APPARDPPARAPPARGKMO | |
| SCHEMBL12320222 | 0.78 | KMT2A (0.57) | KMT2APPARDPPARAPPARGNTSR1 | |
| SCHEMBL14947702 | 0.78 | KMT2A (0.66) | KMT2APPARDPPARAPPARGNTSR1 | |
| SCHEMBL9191040 | 0.78 | KMT2A (0.57) | KMT2APPARDPPARAPPARGITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017121444-A1 | QUINOLIN-2-ONE DERIVATIVES | MERCK PATENT GMBH (DE) | 2017-07-20 | — | — | WO | disclosed |