SCHEMBL19145658

SCHEMBL19145658

CCOc1ccccc1/C=C/c1ccc(N(c2ccc(C)cc2)c2ccc(C)cc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NFE2L2 Q16236 4/20 0.48
RELA Q04206 1/20 0.44
TRPA1 O75762 1/20 0.44
FGF23 Q9GZV9 1/20 0.43
CTDSP1 Q9GZU7 1/20 0.42
CYP1A1 P04798 2/20 0.41
CYP1A2 P05177 2/20 0.41
CYP1B1 Q16678 2/20 0.41
MAPT P10636 5/20 0.41
LMNA P02545 2/20 0.41
ATM Q13315 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
RAB9A P51151 3/20 0.41
NPC1 O15118 2/20 0.41
KMT2A Q03164 1/20 0.41
ALDH1A1 P00352 2/20 0.40
TDP1 Q9NUW8 2/20 0.40
KDM4E B2RXH2 2/20 0.40
NSD2 O96028 1/20 0.40
HTT P42858 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14669771 1.00 NFE2L2 (0.48) NFE2L2RELATRPA1FGF23CTDSP1
SCHEMBL15496861 0.96 NFE2L2 (0.45) NFE2L2RELATRPA1FGF23CTDSP1
SCHEMBL15499125 0.96 NFE2L2 (0.45) NFE2L2RELATRPA1FGF23CTDSP1
SCHEMBL28304597 0.93 NFE2L2 (0.54) NFE2L2RELATRPA1FGF23CYP1A1
SCHEMBL15496805 0.91 NFE2L2 (0.41) NFE2L2RELATRPA1FGF23CTDSP1
SCHEMBL15499117 0.91 RELA (0.50) NFE2L2RELATRPA1CYP1A2MAPT
SCHEMBL15496865 0.88 NFE2L2 (0.39) NFE2L2RELATRPA1FGF23CTDSP1
SCHEMBL15478867 0.85 NFE2L2 (0.38) NFE2L2RELATRPA1FGF23CTDSP1
SCHEMBL12411750 0.85 NFE2L2 (0.63) NFE2L2RELATRPA1FGF23CYP1A1
SCHEMBL15496845 0.85 NFE2L2 (0.38) NFE2L2RELATRPA1FGF23CTDSP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230056801-A1 Electrophotographic Photoreceptor, Electrophotographic Photoreceptor Cartridge, and Image Forming Device MITSUBISHI CHEMICAL CORPORATION (JP) 2023-02-23 US disclosed
US-20170205719-A1 IMAGE FORMING APPARATUS AND ELECTROPHOTOGRAPHIC CARTRIDGE MITSUBISHI CHEMICAL CORPORATION (JP) 2017-07-20 US disclosed