Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 11/20 | 0.59 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.59 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.59 |
| ▸ | PSMB1 | P20618 | 3/20 | 0.58 |
| ▸ | PSMB5 | P28074 | 3/20 | 0.58 |
| ▸ | PSMB2 | P49721 | 2/20 | 0.58 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3398839 | 0.82 | NPC1 (0.59) | LTA4HPSMB1PSMB5PSMB2HRH3 | |
| SCHEMBL7353075 | 0.81 | PSMB1 (0.66) | LTA4HPTGS2PSMB1PSMB5PSMB2 | |
| SCHEMBL23742244 | 0.79 | PSMB1 (0.69) | LTA4HPSMB1PSMB5PSMB2HRH3 | |
| SCHEMBL56495 | 0.78 | LTA4H (0.90) | LTA4HPTGS2PTGS1PSMB1PSMB5 | |
| SCHEMBL4167205 | 0.78 | PSMB1 (0.60) | LTA4HPSMB1PSMB5PSMB2HRH3 | |
| SCHEMBL11877770 | 0.78 | HRH3 (0.83) | LTA4HPSMB1PSMB5HRH3 | |
| SCHEMBL3589376 | 0.78 | HRH3 (0.68) | LTA4HPSMB1PSMB5PSMB2HRH3 | |
| SCHEMBL13883476 | 0.78 | HRH3 (0.61) | LTA4HPTGS2PTGS1PSMB1PSMB5 | |
| SCHEMBL3611053 | 0.78 | HRH3 (0.61) | LTA4HPTGS2PTGS1PSMB1PSMB5 | |
| SCHEMBL11882995 | 0.77 | HRH3 (0.86) | LTA4HPSMB1PSMB5PSMB2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017121444-A1 | QUINOLIN-2-ONE DERIVATIVES | MERCK PATENT GMBH (DE) | 2017-07-20 | — | — | WO | disclosed |