Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 4/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 3/20 | 0.44 |
| ▸ | RIN1 | Q13671 | 3/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.42 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.42 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.42 |
| ▸ | NR2F2 | P24468 | 2/20 | 0.42 |
| ▸ | GALR3 | O60755 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21540034 | 0.90 | P2RY12 (0.44) | P2RY12CYP1A2PRMT6ABL1RIN1 | |
| SCHEMBL25293 | 0.90 | P2RY12 (0.48) | P2RY12P2RY2P2RY1P2RY6 | |
| SCHEMBL21726069 | 0.89 | P2RY12 (0.55) | P2RY12P2RY2P2RY1P2RY6 | |
| SCHEMBL21263848 | 0.89 | P2RY12 (0.44) | P2RY12CYP1A2PRMT6ABL1RIN1 | |
| SCHEMBL19343832 | 0.89 | ABL1 (0.56) | CYP1A2ABL1RIN1NR2F2GALR3 | |
| SCHEMBL25004 | 0.89 | ABL1 (0.56) | CYP1A2ABL1RIN1NR2F2GALR3 | |
| SCHEMBL12652414 | 0.89 | UBA6 (0.47) | P2RY12CYP1A2PRMT6ABL1RIN1 | |
| SCHEMBL20692061 | 0.88 | P2RY12 (0.45) | P2RY12P2RY2P2RY1P2RY6 | |
| SCHEMBL19146448 | 0.88 | CYP1A2 (0.48) | P2RY12CYP1A2PRMT6ABL1RIN1 | |
| SCHEMBL23621388 | 0.88 | P2RY12 (0.44) | P2RY12CYP1A2PRMT6ABL1RIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017123669-A1 | CYCLIC DINUCLEOTIDES FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY SUCH AS CANCER | GLICK GARY (US) | 2017-07-20 | — | — | WO | disclosed |