Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | ABL1 | P00519 | 4/20 | 0.46 |
| ▸ | RIN1 | Q13671 | 4/20 | 0.46 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.46 |
| ▸ | NR2F2 | P24468 | 2/20 | 0.44 |
| ▸ | GALR3 | O60755 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19343832 | 0.91 | ABL1 (0.56) | CYP1A2ABL1RIN1NR2F2GALR3 | |
| SCHEMBL25004 | 0.91 | ABL1 (0.56) | CYP1A2ABL1RIN1NR2F2GALR3 | |
| SCHEMBL13965624 | 0.89 | PRMT6 (0.44) | ABL1RIN1PRMT6P2RY12 | |
| SCHEMBL19146385 | 0.88 | CYP1A2 (0.44) | CYP1A2ABL1RIN1PRMT6NR2F2 | |
| SCHEMBL19146239 | 0.88 | P2RY12 (0.44) | CYP1A2ABL1RIN1PRMT6NR2F2 | |
| SCHEMBL12652414 | 0.87 | UBA6 (0.47) | CYP1A2ABL1RIN1PRMT6NR2F2 | |
| SCHEMBL21540034 | 0.87 | P2RY12 (0.44) | CYP1A2ABL1RIN1PRMT6NR2F2 | |
| SCHEMBL21726069 | 0.86 | P2RY12 (0.55) | P2RY12 | |
| SCHEMBL22907485 | 0.86 | CYP1A2 (0.43) | CYP1A2ABL1RIN1PRMT6NR2F2 | |
| SCHEMBL20792252 | 0.85 | ADORA3 (0.44) | PRMT6NPC1RAB9ASMN1; SMN2P2RY12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017123669-A1 | CYCLIC DINUCLEOTIDES FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY SUCH AS CANCER | GLICK GARY (US) | 2017-07-20 | — | — | WO | disclosed |