SCHEMBL19147165

SCHEMBL19147165

CO[C@@H]1[C@H](OP(=O)(O)OC[C@H]2C[C@H](n3cc(C)c(=O)[nH]c3=O)O[C@@H]2CO)[C@@H](COP(=O)(S)O[C@H]2[C@@H](C)[C@H](n3cnc4c(N)ncnc43)O[C@@H]2COP(=O)(S)OC(C)C)O[C@H]1n1cnc2c(N)ncnc21

nearest known ligand 0.55

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ DTYMK P23919 4/20 0.55
▸ RNASEL Q05823 7/20 0.47
▸ TERT O14746 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19146305 0.95 DTYMK (0.58) DTYMKRNASEL
SCHEMBL19152085 0.94 DTYMK (0.54) DTYMKRNASELTERT
SCHEMBL19152966 0.89 DTYMK (0.57) DTYMKRNASELTERT
SCHEMBL19147041 0.86 DTYMK (0.59) DTYMKRNASELTERT
SCHEMBL19147053 0.85 DTYMK (0.58) DTYMKRNASELTERT
SCHEMBL24325350 0.84 DTYMK (0.58) DTYMKRNASELTERT
SCHEMBL19147022 0.83 DTYMK (0.62) DTYMKRNASELTERT
SCHEMBL27062487 0.80 DTYMK (0.59) DTYMKRNASELTERT
SCHEMBL17775302 0.80 DTYMK (0.54) DTYMKRNASEL
SCHEMBL27000669 0.79 DTYMK (0.54) DTYMKRNASELTERT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170204152-A1 CHIMERIC POLYNUCLEOTIDES MODERNA THERAPEUTICS, INC. (US) 2017-07-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170204152-A1 CHIMERIC POLYNUCLEOTIDES NSUN3, TRDMT1, NSUN2 DTYMK 156/4885RNASEL 170/4885TERT 87/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback