SCHEMBL19146305

SCHEMBL19146305

CO[C@@H]1[C@H](OP(=O)(O)OC[C@H]2C[C@H](n3cc(C)c(=O)[nH]c3=O)O[C@@H]2CO)[C@@H](COP(=O)(O)O[C@H]2[C@@H](C)[C@H](n3cnc4c(N)ncnc43)O[C@@H]2COP(=O)(O)OC(C)C)O[C@H]1n1cnc2c(N)ncnc21

nearest known ligand 0.58

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ DTYMK P23919 4/20 0.58
▸ RNASEL Q05823 9/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19147165 0.95 DTYMK (0.55) DTYMKRNASEL
SCHEMBL19152966 0.94 DTYMK (0.57) DTYMKRNASEL
SCHEMBL19147041 0.89 DTYMK (0.59) DTYMKRNASEL
SCHEMBL19152085 0.88 DTYMK (0.54) DTYMKRNASEL
SCHEMBL19147022 0.86 DTYMK (0.62) DTYMKRNASEL
SCHEMBL19147053 0.81 DTYMK (0.58) DTYMKRNASEL
SCHEMBL24325350 0.81 DTYMK (0.58) DTYMKRNASEL
SCHEMBL19129897 0.81 RNASEL (0.47) RNASEL
SCHEMBL29306731 0.80 DTYMK (0.69) DTYMKRNASEL
SCHEMBL25912829 0.80 DTYMK (0.69) DTYMKRNASEL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170204152-A1 CHIMERIC POLYNUCLEOTIDES MODERNA THERAPEUTICS, INC. (US) 2017-07-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170204152-A1 CHIMERIC POLYNUCLEOTIDES NSUN3, TRDMT1, NSUN2 DTYMK 156/4885RNASEL 170/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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