Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 2/20 | 0.64 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.64 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | IGF1R | P08069 | 6/20 | 0.43 |
| ▸ | NT5E | P21589 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19150082 | 0.87 | ADORA2A (0.68) | ADORA2AADORA1TLR7ADRB2KMT2A | |
| SCHEMBL19149239 | 0.84 | ADORA2A (0.64) | ADORA2AADORA1TLR7ADRB2KMT2A | |
| SCHEMBL8229246 | 0.82 | ADORA2A (0.66) | ADORA2AADORA1TLR7ADRB2KMT2A | |
| SCHEMBL19149165 | 0.81 | NT5E (0.48) | ADORA2AADORA1TLR7ADRB2KMT2A | |
| SCHEMBL8441818 | 0.79 | ADORA2A (0.71) | ADORA2AADORA1TLR7ADRB2KMT2A | |
| SCHEMBL7226777 | 0.78 | ADORA2A (1.00) | ADORA2AADORA1TLR7ADRB2KMT2A | |
| SCHEMBL693661 | 0.78 | NT5E (0.62) | ADORA2AADORA1TLR7ADRB2KMT2A | |
| SCHEMBL5550207 | 0.77 | ADORA2A (0.59) | ADORA2AADORA1TLR7ADRB2KMT2A | |
| SCHEMBL19148204 | 0.77 | MAOA (0.38) | ADORA2AADORA1KMT2AMAPTGAA | |
| SCHEMBL28311336 | 0.74 | ADORA2A (0.55) | ADORA2AADORA1TLR7ADRB2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10266494-B2 | Process for the preparation of polyfluoroalkylated quinolines | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-04-23 | — | — | US | disclosed |
| US-20190023659-A1 | PROCESS FOR THE PREPARATION OF POLYFLUOROALKYLATED QUINOLINES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-01-24 | — | — | US | disclosed |
| EP-3405458-A1 | PROCESS FOR THE PREPARATION OF POLYFLUOROALKYLATED QUINOLINES | Bayer CropScience Aktiengesellschaft (DE) | 2018-11-28 | — | — | EP | disclosed |
| WO-2017125318-A1 | PROCESS FOR THE PREPARATION OF POLYFLUOROALKYLATED QUINOLINES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-07-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190023659-A1 | PROCESS FOR THE PREPARATION OF POLYFLUOROALKYLATED QUINOLINES | KCNQ1, KCNQ2, KCNQ4 | ADORA2A 2373/4885ADORA1 3242/4885TLR7 356/4885 |
| US-10266494-B2 | Process for the preparation of polyfluoroalkylated quinolines | KCNQ1, KCNQ2, KCNQ4 | ADORA2A 2373/4885ADORA1 3242/4885TLR7 356/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.