SCHEMBL19149558

SCHEMBL19149558

C=C(C)c1ccccc1.C=C(C=O)c1ccccc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.45
MAPK1 P28482 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
TSHR P16473 3/20 0.41
CES2 O00748 4/20 0.40
CES1 P23141 4/20 0.40
AKT1 P31749 1/20 0.39
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
LMNA P02545 1/20 0.38
MAPT P10636 1/20 0.38
XBP1 P17861 1/20 0.38
ATM Q13315 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
KDM4E B2RXH2 1/20 0.36
ELANE P08246 1/20 0.36
NAPRT Q6XQN6 2/20 0.36
DAO P14920 1/20 0.36
EGFR P00533 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL58595 0.89 ALDH1A1 (0.54) ALDH1A1MAPK1TDP1TSHRCES2
Formic Acid SCHEMBL7160950 0.85 CES2 (0.44) ALDH1A1MAPK1TDP1TSHRCES2
Acetaldehyde SCHEMBL5163139 0.85 CES2 (0.44) ALDH1A1MAPK1TDP1TSHRCES2
SCHEMBL472891 0.82 CES2 (0.48) ALDH1A1TSHRCES2CES1AKT1
SCHEMBL2905282 0.82
SCHEMBL1331472 0.82
Benzene SCHEMBL28197619 0.82 CES2 (0.48) ALDH1A1TSHRCES2CES1AKT1
SCHEMBL6577 0.82
Hydrogen Peroxide SCHEMBL7249472 0.82 CES2 (0.48) ALDH1A1TSHRCES2CES1AKT1
SCHEMBL3267692 0.82 CES2 (0.48) ALDH1A1TSHRCES2CES1AKT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017127728-A1 OZONE-ACTIVATED NANOPOROUS GOLD AND METHODS OF ITS USE PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2017-07-27 WO disclosed